Clinic Study On The Treatment Of Ankylosing Spondylitis Of Cold-dampness Syndrome With Juan Bi Gao And Its Decomposed Recipe

Objective: To investigate the clinical effect and safety of Juan Bi Gao (JBG) on the treatment of Ankylosing Spondylitis (AS) of cold-dampness syndrome, meanwhile, to explore feasibility of clinic prescription compatibility research through observing the effect of the drugs having the property of promoting blood circulation in JBG as JBG and the compound recipe called Qu Feng Han Shi Gao (QFHSG) were used. QFHSG is JBG's decomposed compound recipe excluding the drugs having the property of promoting blood circulation. Methods: Sixty-one cases with AS of cold-dampness syndrome were randomly divided into three groups: JBG sticking treatment group(group JBG), QFHSG sticking treatment group(group QFHSG) and a control group (only treated with SASP 500mg t.i.d /per day) and twenty-two cases for group JBG, twenty cases for group QFHSG, nineteen cases for control group. Aside from external drugs, group JBG and group QFHSG received the same western medicine treatment as control groups'. The treatment lasted one month, and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Function Index (BASFI), score on the pain of lower waist and back, Schober test, time of morning stiffness, distance of middle-finger to floor, ESR, CRP were measured before and after treatment. Results: The total effective rate of group JBG, group QFSHG and control group was 63.64%, 52.63%, 42.11% respectively that was no significant difference among them (p>0.05). Group JBG decreased significantly score on the pain of lower waist and back, distance of...