Effects Of Stellate Ganglion Blockade On Oleic Acid Induced Acute Lung Injury In Rabbits

Objective: Acute Lung Injury (ALI) is the early phase of the acute respiratory distress syndrome (ARDS). Some factors such as infection, trauma and shock resulted to pulmonary edema and segmental atelectasis. With the development of Immunology and molecular biology, the study of the pathogenesis of ALI was almost focused on the aspect of the injury to the lung of cytokine. However, the morbidity and mortality is still high, and frequently, ALI/ARDS is the complication of the brain injured such as trauma, hemorrhage, cerebral anoxia, indicated that the nuerofactors is important to the development of ALI/ARDS.Stellate ganglion block (SGB) is a curative technique that involves injection of the stellate ganglion with local anesthetic solution. The stellate ganglion is a sympathetic ganglion located anteroinferiorly to the transverse process of the seventh cervical vertebra (C7). The clinical indications for SGB has been extended to many diseases with the study of it, SGB is usually used to treatment the lung diseases such as chronic bronchitis, asthma, pulmonary hypertension, however, whether SGB iseffective to ALI still need to study.This experiment was conducted to determine whether SGB...