Comparative Study On The Variation Of Carotid Intima-media Thickness And Ankle-brachial Index Levels In Coronary Heart Disease Patients Underwent Percutaneous Coronary Intervention

Objective This study investigated the variation of carotid intima- media thickness(IMT)and ankle-brachial index(ABI)levels in coronary heart disease(CHD) patients before and after percutaneous coronary intervention(PCI)to evaluate their relationships with CHD and clinical signification of diagnosis and treatment in CHD comparatively.Methods 57 patients who underwent PCI and successfully completed six months of follow-up observation were enrolled.Their IMT,ABI were measured and serum total cholesterol(TC),triglycerides(TG),low- density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C)were determined before and after PCI.Results 1.The IMT significantly decreased from 1.13±0.27(mm)before PCI to 1.04±0.21(mm)after PCI(P＜0.01),and the positive rate of it(≥1.00mm) decreased from 73.68%to 54.39%(P＜0.05).2.The ABI signifi- cantly increased from 0.91±0.07 before PCI to 0.94±0.05 after PCI(P＜0.01),and the positive rate of it(≤0.90)decreased from 47.36%to 24.56%(P＜0.05).3.The decreases of TC,TG and LDL-C were signify- cantly higher after PCI than that before(P＜0.001),they were 5.43±1.29,1.93±1.01,3.75±1.20(mmol/L)separately before PCI and were 5.08±0.67,1.80±0.79,3.36±0.58(mmol/L)separately after PCI;The increases of HDL-C was significantly higher after PCI than that before(P＜0.01),they were 1.03±0.35,1.08±0.29(mmol/L)separately.Conclusion Both IMT and ABI are significantly correlated with extent of coronary heart disease and can be used as non-intrusive,simple and effective methods of diagnosing,monitoring and tracking the progress of coronary atherosclerosis.