The Appropriate Cut-off Point Of Waist Circumference Of Uigurs For Identifying Metabolic Syndrome In Chinese Adults

Objective: To analyze the appropriate cut-off point of waist circumference of Uigurs for identifying metabolic syndrome(MS) in Chinese adults. Methods: Based on the IDF consensus worldwide definition of the metabolic syndrome,subjects of 2526 Uigurs adults with 25-90 years from Urmuqi city and Kashgar region were used to analyze the ORs of clustering of MS components by different strata of waist circumference. The sensitivity,specificity and distance in ROC curve by different cut-offs of waist circumference for identifying two components of MS were estimated to find the cut-off point for males and females in Uigurs with the shortest distance in ROC curve. Resuts: (1) The ORs of clustering of MS components increased significantly with the size of waist circumference. The waist circumference (≥93 cm for men,≥89cm for women) corresponded to the shortest distance in ROC curve,namely,at these cut-offs,the rates of false positive and false negative for identifying MS were the minimum. The prevalence of MS was 26.0% and 27.7% in men and women respectively.(2) The level of waist circumference of Uigurs adults were high,and there was significant difference between youth and the aged(P<0.01).The relation between the waist circumference and the age was closer in female than in male. Conclusions: The waist circumference(≥93cm for men,≥89cm for women) were the appropriate cut-off points of Uigurs for identifying MS.This recommendation needs further confirmation in a larger sample group of Uigurs.