Relation Of Ankle Brachial Index With The Other Risk Factors For Discussion

IntroductionNow the whole world has the nearly 1/4 population threatens for thecardiovascular and correlation disease. In our country recent years, along with lives ofthe people level enhancement, life style change, Chinese cardiovascular diseasedangerous factor levels and so on body weight index, blood pressure, cholesterol, diabetes have the obvious increase and assume advance continually the tendency.Cardiovascular disease disease incidence rate also assumes the obvious rise to hasten.Forecast according to the World Health Organization, to 2020, the non-communicabledisease will occupy our country cause of death 79%, in which cardiovascular diseasewill occupy the first place. At present appraised the cardiovascular disease risk and theprognosis traditional method is not ideal, therefore discussed the new method to raisethe program. Recently in the cardiovascular domain malleolus - arm blood pressureindex (ankle-brachial index, ABI) took one kind not creates the survey method toreceive more and more pays attention. In this research we draw up to ABI andcardiovascular disease during dangerous factor relations carry on the preliminarydiscussion. Is for the purpose of understanding ABI takes the new dangerous factorforecast target and other cardiovascular disease during dangerous factor relations and inthe crowd cardiovascular disease morbidity clinical significance.Methods1.Subject(1)Patients: A total of 100 patients were selected from1, 2006 to7, 2007 in the ninthhospital of shenyang. There are coroaryatherosclerotic heart diease, diabetes mellitus and cerebral vascular disease in the patients. Selecting ABI≤1.4 patients forobject, average age of (66.63±6.5) years.There are 49 males and 51 females. Accordingto the sexual distinction and ABI, these patients were divided.(2)Healthy controls: 20 outpatients were selected, including 10men and 10 womenwith a mean age of (66.70±6.3) years.2.Research methods(1)General data: detailed inquiry medical history, life style and behavior, menstruation history, family history.(2)Physical examin: BMI index determination, malleolus elbow blood pressure, heart rate, heart rhythm, electrocardiogram (normal; ST-Tchange; Cardiac arrest; FangChan; Other arrythmias; The left room is plump; Fang Zao; PR time; The atriumsinistrum expansion atrium dextrum expands) and so on.(3)Sample collection: In hospitalized second date early morning 6 o'clock drawsblood 4ml, measures blood serum total cholesterol (TC), triglyceride (TG), high densitylipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), emptystomach blood sugar (FBG).The same day measures OGTT 2 hours blood sugars.(4) Measuring and judging of ABI: Measureing the pressure of the arm and theankle and using the pressure of the ankle comparetive the pressure of the arm. Selectingthe low data was the ABI data. ABI＜0.9 was judging abnormal. 0.9≤ABI≤1.4 wasjudging normal. ABI＞1.4 judgment for calcification and elimination research crowd(5)Statistical analysis: All the data were processed by SPSS10.0 for windows.Themeasurement dta were expressed by mean±standard deviatin((?)±s) and the groupcomparison was performed by tow-sample, non-paired data t test. The numerationdatawere compared by Chi square test. The relationship of ABI with the other risk factorsof CVD was analyzed by single analysis andmultivariate Logistic. If P value was lessthan 0.05, the difference was considerd statistically significant.Results1. The research crowd and the healthy control group ABI observed valuecompares: The research crowd group ABI observed value (1.05±0.07) is lower than thehealthy control group ABI observed value (1.09±0.08), during two groups comparesuses the T-test (t=2.256, P=0.024), during two groups has the difference. 2. The research crowd group male and the feminine ABI＜0.9 formation ratecomparison and the male and the feminine ABI value compare: The research crowdgroup male 49 people, in which ABI＜0.9 is 15 examples; The feminine 51 people, inwhich ABI＜0.9 is 16 examples, during two groups uses X~2 the examination (X~2=0.018, P＞0.05), during two groups does not have the difference.The masculine group ABIvalue for 1.03±0.06 the feminine group ABI value for 1.06±0.08, during two groupscompares uses the T-test (t=3.0, P=0.003), during two groups has the difference.3. The research crowd group masculine ABI＜0.9 group compares with ABI≥0.9the group each cardiovascular disease dangerous factor observed value: The researchcrowd group male 49 people, in which ABI＜0.9 is 15 examples, 0.9≤ABI≤1.4 is 34example during two groups compares the ABI＜0.9 group in the age, the blood sugarvalue, the blood pressure value, smoking rate compares both with 0.9≤ABI≤1.4 thegroup to have the remarkable statistics significance.4. The research crowd group feminine ABI＜0.9 group compares with ABI≥0.9 thegroup each cardiovascular disease dangerous factor observed value: The research crowdgroup female 51 people, in which ABI＜0.9 is 16 examples, 0.9≤ABI≤1.4 is 35 exampleduring two groups compares the ABI＜0.9 group in the age, the blood sugar value, smoking rate compares both with 0.9≤ABI≤1.4 the group to have the remarkablestatistics significance.5. Logistic regression analysis research crowd ABI decreases with thecardiovascular during dangerous factor the relevance: Establishes the Logistic returnmodel, carries on the correlation analysis demonstration sex, hypertension, diabetes, smoking for the low ABI(ABI＜0.9) major effect factor.DiscussionThe vascular disease has become threatens the human health the serious problem, Therefore into the cardiovascular academic circles pays attention now to the arterystructure and the function change assessment method and the prognosis significanceresearch hot spot. The dangerous factor research is one of its hot spots, Inmultitudinous new dangerous factor family, ABI is one of them.The overseas many large-scale clinical research confirmed ABI is diagnoses thecircumference artery disease (even in has not had in front of symptom), appraised its prognosis simple, effective, not creates method. But in the cardiovascular domaindiscovered similarly ABI has reflected the coronary artery pathological change degree.It exceptionally also indicates the future will have the cardiovascular event or the deathrisk can have the obvious markup.This article studies demonstrated ABI has the accumulation relations with othercardiovascular disease during dangerous factor. Correlations and so on ABI and age, diabetes medical history, smoking history, hypertension; The ABI value reduces theincrease cardiovascular disease the morbidity danger. Must further positively search thecorrelation dangerous factor to the clinical discovery low ABI patient, Carries on theoverall assessment and the intervention to many kinds of dangerous factors obtains thebest treatment result.Conclusion1.This research indicates ABI and the sex, hypertension, diabetes, the smokingcorrelation.2. The age, the blood sugar value, the blood pressure value, smoking rate theprimary dangerous factor which decreases for the male. The feminine ABI unusualcorrelation dangerous factor has the age, the blood sugar value, smoking rate.3. ABI＜0.9 may increase cardiovascular disease the morbidity danger, Clinicalshould take the low ABI monitor, By time early time discovery cardiovascular diseaseexistence, Intervenes the treatment positively.