Effect Of Chunxiangcaocongerpian On NO,ET In Patients With Sudden Deafness

Objective: To investigate the Effect Of Chunxiangcaocongerpian On NO?ET In Patients With Sudden Deafness Method: 91 Sudden Deafness patients were randomized into two groups, 48 cases as treatment group, in which a basic treatment combined with Chunxiangcaocongerpian, 43 cases as controlled group, with a basic treatment. One courses of treatment which lasted for 14 days were undergone. While observing the level of lisening, we measure the levels of NO and ET before and after therapy in these two groups. The curative effectiveness was evaluated. Results: After 14 days treatment, two groups improve the level of lisening (86.21% in treatment group, 71.12% in controlled group), The discrepancy in two groups have no signifcance of statistics before treatment (P>0.05). However, the levels of lisening were significance in the two groups (P<0.01). There was no significant difference in NO and ET among two groups before treatment (P>0.05). After treatment, the levels of NO were obviously lncreased in treatment group (P<0.01). the levels of ET were obviously decreased in treatment group (P<0.01). the levels of NO were obviously lncreased in controlled group (P<0.01), the levels of ET were obviously decreased in controlled group (P<0.01). Conclusions: Chunxiangchaochongerpian can not only improve the level of lisening of Sudden Deafness patients, but aslo evidently increase the levels of No and decreace levels of ET. There fore, It can dilate blood vessels in order to improve cochlear microcirculation. The function of being injured cochlear hair cells will recovered. That is one of mechanisms curing Sudden Deafness.