Analysis Of Pregnancy Outcomes On 124 Cases With Preterm Premature Rupture Of Membranes

Objective:Objective to evaluate the risk factors,clinical management and pregnancy outcome in pregnancy complicated with preterm premature rupture of membranes(PPROM)。Methods:The clinical data of 124 patients with premature rupture of membranes in the first affiliated hospital of Dalian Medical University from January 2002 to December 2007 were retrospective study。44 patients with preterm premature rupture of the membranes at 28-33⁺⁶ weeks were selected as group A, while 88 patients with premature rupture of membranes at 34-36⁺⁶ weeks as group B。At the same time randomly selected full-term pregnancy with unbroken membranes hospitalized in the same period, 248 cases was as contrast group for comparison.Results:90.3% PPROM had predisposing factors。In patients at 28-33⁺⁶ weeks gestation with 34-36⁺⁶ weeks gestation on PPROM,the puerperal infection,postpartum hemorrhage and delivery methods was no statistically differences(P>0.05)。The postpartum hemorrhage of PPROM group compared with the full-term delivery, the difference was statistically significant(P<0.05)。The latent period≤24 hours with latent period>24 hours on the patients at 28-33⁺⁶ weeks of PPROM,the asphyxiated newborns was statistically differences(P<0.05)。The latent period>24 hours with latent period≤24 hours on the patients at 34-36⁺⁶ weeks of PPROM,the neonatal infection was statistically difference(sP<0.05)。The asphyxiated newborns and perinatal mortality were higher in 28-33⁺⁶ weeks gestation than 34-36⁺⁶ weeks gestation,the difference was statistically significant(P<0.05)。Conclusions:Active treatment of complications of the perinatal and pregnant period is important to reduce neonatal complications and maternal infection,and to improve the optimum quality。The treatment scheme should be made according to the patients'pregnant week,and modified to fit different patients。Pregnancy between 28 and 35 weeks' gestation with preterm premature rupture of membranes should be managed expectantly to reduce neonatal complications , including the correct application of uterine contraction,steroids and antibiotics。we should pay more attention to PPROM in different gestational age,choosing the appropriate selection of the moment and proper delivery mode of terming pregnancy are help for mother and fetus。...