Clinical Analysis Of 198 Cases Of Preterm Premature Rupture Of Membranes

Objective:Preterm premature rupture of membranes was observed birth outcomes and the influence of the newborn. Understand the impact of latency period, gestational age and the start time of prophylactic antibiotics on birth outcomes and neonatal outcomes.Methods:Choose 259 cases of preterm labor with intact membranes and 198 cases of preterm premature rupture of membranes who have treatment in Subei People Hospital from 2010 to 2014. Observe the mode of delivery and Neonatal outcomes of preterm premature rupture of membranes and non preterm premature rupture of membranes. On selected 198 cases of preterm premature rupture of maternal and neonatal, Observe different latencies, different gestational age and different from the rupture time to start using antibiotics, impact on the mode of delivery and neonatal outcomes.Results:The incidence of preterm premature rupture of membranes in pregnant women is 43%, premature rupture of membranes is an important cause of preterm delivery. Compare with fetal distress, and asphyxia rate preterm premature rupture of membranes and non preterm premature rupture of membranes. The difference was not statistically significant (P> 0.05). But Cesarean section rate in both groups, the rate of neonatal lung injury, neonatal infection, pneumonia rate of neonatal and neonatal hyperbilirubinemia rate statistically significant (P<0.05). Compare gestational age of 28 to 34+6 weeks group and 35 to 36+6 weeks of fetal distress group, neonatal asphyxia, neonatal lung injury, neonatal infection, pneumonia, neonatal and neonatal hyperbilirubinemia, found that neonatal asphyxia, neonatal lung injury, and neonatal hyperbilirubinemia differences were statistically significant (P<0.05), but Two sets of fetal distress, neonatal infection, and there was no comparison of neonatal pneumonia statistically significant (P> 0.05); After comparison the latency period≤24h and the latency period> 24 group obtained, cesarean section rate, neonatal asphyxia rate, neonatal lung injury rate, neonatal infection, neonatal pneumonia rate differences were statistically significant (P<0.05). Two groups of fetal distress and neonatal hyperbilirubinemia, the difference was not statistically significant (P> 0.05); The time from rupture to start using antibiotics≤12h to start using antibiotics and rupture time> 12h rate of two fetal distress, neonatal infection, neonatal pneumonia rate comparison, the difference was statistically significant (P<0.05). Two groups of neonatal asphyxia, neonatal lung injury rate and neonatal hyperbilirubinemia rate was not statistically significant (P> 0.05).Conclusion:(1) PROM is one important reason of preterm, preterm premature rupture of membranes more likely to lead to dystocia and neonatal complications. Therefore, we should pay attention to the treatment of pregnant women PPROM.(2) Preterm premature rupture of the newborn, gestational age is smaller, fetal distress, neonatal asphyxia, the greater the likelihood of lung injury, Therefore, we should in the absence of maternal and fetal infection, fetal distress, as far as the treatment of miscarriage promote fetal lung maturity.(3) To the PPROM pregnant women, we should try to extend the latency period, but also can increase latency prolonged neonatal infection and neonatal pneumonia. We found earlier prophylactic use of antibiotics can reduce fetal distress, neonatal infection, and neonatal pneumonia. We should fully grasp the balance between treatment and termination of pregnancy miscarriage.