| Hemorrhagc Fever with Renal Syndrime(HFRS)is a natural focus disease,and it prevails in Asia and Europe,Epidemic hemorrhagic fever(EHF,one kind of HFRS) often occurs in some areas of the Asia,mostly in China.HFRS is causes by the Hantan virus,researchs confirmed the virus was divides into 9 typies,At present,Hantan and Seoul.type are popular in China,and HFRS epidemics still serious in our country, and it also appeares new epidemic characteristics:①The number of HFRS patients is rising obviously;②Old epidemic areas' scope expanded,the new epedemic areas appeared continually.③The big and media-sized cities' epidemic intensity rising,the disease is spreading to the big and media-sized cities.④The epidemic seasonal characteristics changed obviously,besides the winter,HFRS occurs has no difference in other seasons.Objective:The Junan county is a plain low elevation area,and full of rivers;Pingyi County is a typical mountain area with only a few rivers,the elevation is higher.The distance of two counties is about 100 kilometers,but ecological environments are very different.Their epidemic of HFRS are all serious,and they are all our countrys' HFRS monitoring points.This research plans to use the two counties' HFRS mornitoring materials to unifies geographical environment,ecology characteristic,and so on,with epidemiology research technique,to analyze the difference of spatial structure and propose theories to HFRS in same areas in order to prevent and control the disease. Results from this study showed that:1.In Junan county 16118 HFRS patients occured from 1975～2005 altogether,the average incidence rate 58.61/100,000,203 people died of the illness,average mortality rate 1.26%.Man account for 67.24%,88.05%patients' age from 15 to 64, farmers account for 88.92%,is the highest proportion among the case;In Pingyi County 9384 patients of HFRS occurred from 1980.11 to 2005.11,the average disease incidence rate 29.48/100,000,265 were died of the illness,average fatality rate 2.82%.The male accounts for 64.96%,patients among 35～45 years old account for the highest proportion(33.23%);farmers accounts for 88.99%.2.The epidemic characters of HFRS in the two counties varied periodictly, Pingyi County epidemic cycle approximately 3～5 years,the Junan county approximately 5～7 years.Morbidity seasonal characer,the two counties each experienced a single peak of fall and winter type~→double peaks of fall and winter type~→double peaks of spring type.As a whole,the two county HFRS fatality rate in autumn and winter season is bigger than spring,the tendency of case fatality rate dropped by time.3.Epidemic areas in the two counties have followed four stages:meadow mouse caused highly sporadic stage~→meadow mouse caused mixed type outbreak stage~→house and meadow mouse mixed type highly sporadic stage~→house mouse primarily mixed type outbreak stage~→house mouse primarily caused mixed type highly sporadic stage.Till December,2005,the two counties' HFRS still in the mixed type stage primary caused by house mouse.Fieldmouse peak occurs in September to February of the next year,house mouse peak occurs in March to May.The mouse density peak occurs in the third quarter,the mouse' poison rate in 4th quarter is the highest.4.The case of HFRS has the obvious accumulation distribution between towns of the two counties.The high incidence areas are often located in low plains which full of rivers;The medium incidence areas mainly locate in the dry and low wooded mountain areas;The low incidence areas distribute in the high elevation mountain areas.At the same time,incident in the two counties also has family accumulation phenomenon.Conclusion:1.The two counties epidemic areas experienced:HTN type~→fixed HTN type~→fixed SEO type,and the two counties all have five followed epidemic stages:highly sporad→local epidemic→outbreak→extensive epidemic→highly sporadic.The two counties' fatality rate droped continuously with time,fatality rates in autumn and winter season is higer than spring times.2.There is difference between annual incidence rate and fatality rates.The Junan county's annual incidence rate is higher than Pingyi County,but fatality rate is lower; The HFRS epidemic characters of HFRS in the two counties varied periodictly,and the period in Pingyi County occurs approximately 3～5 years,but in Junan County,it occurs approximately 5～7 years.3.Incidence rate of HFRS in the two counties varied from geography and ecological. In the Linyi municipal,the epidemic areas of HFRS migrated from southeast plain areas which full of rivers to the northwest mountainous areas. |
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