Observing The Curative Effect Of The Traditional Chinese Herb Medicine Jiaweilingguizhugan Decoction On The Disease Of Congestive Heart Failure

OBJECTIVE:Observes doctor practicing western medicine convention treatment+ addition and subtraction water chestnut Gui Zhugan soup treatment chronic congested heart failure(CHF) in the clinical symptoms alleviation,the heart function improvement,contrasts it with the western medicine convention treatment result,is the two difference whether remarkable,thus provides certain fundamental research for the traditional Chinese medicine treatment chronic congested heart failure.METHODS:60 patients with the standards included in patients with congestive heart failure were randomly divided into treatment and control groups,each of the 30 cases. Regulating the control group used traditional western medicine treatment:The application of the latest "chronic congestive heart failure treatment recommendations"(China cardiovascular disease magazine,2002;30(1):7-21) Recommend the most appropriate method of treatment, According to patients after hospital-based treatment of illness:①general routine treatment: rest,salt restriction,oxygen,etc.;②to the diuretic(urine dihydrochloride grams thiadiazole 25～50 mg or 20 mg furosemide,antisterone 20 mg,1 to 3 times daily oral);③ACEI: (captopril 625 mg,twice daily beginning);④β-receptor blocker(metoprolol from 6.25 mg daily oral dose of 1 start);⑤cardio(digoxin 0.25 mg daily oral administration,a week after the condition of patients based on the alignment of their drug dosage or suspension).Western medicine in the treatment group on the basis of standard treatment,Modified oral Lingguizhugan Decoction of treatment,a daily,the course on the 21st.Before and after the treatment clinical symptoms,signs and the total effective rate,left ventricular ejection fraction (LVEF),the changes in blood BNP,And do statistical analysis to compare their efficacy.Results:(1) After treatment group and control group patient's clinical symptoms, heart function treatment,has the enhancement,compares before the treatment,the difference has statistics significance(P＜0.05).(2) After the treatment,treats the group patient's left room to shoot the menstruation number,blood BNP and the control group compares the difference to have statistics significance(P＜0.05). (3) Comparison of the two groups before and after treatment,BNP levels in the blood were significantly different(P＜0.05,P＜0.01),in which the treatment group compared with the control group had a significant difference(P＜0.05),the treatment group than the control group.(4) Hypokalemia the treatment group than the control group,statistical significance(P＜0.05);The withdrawal rate of the treatment group than the control group,a statistically significant(P＜0.05).Conclusions:(1) The doctor practicing western medicine convention treatment and doctor practicing western medicine convention treatment+addition and subtraction water chestnut Gui Zhugan the soup treatment may improve the chronic congested heart failure patient's clinical symptoms and the heart function.(2) Doctor practicing western medicine convention treatment+addition and subtraction water chestnut Gui Zhugan the soup treatment compares the doctor practicing western medicine convention treatment curative effect to be good..(3) Effects of jiaweiLingguizhugan decoction can significantly reduce plasma BNP levels,which play a role in myocardial protection.(4) Integrated Treatment of a purely western medicine can better reduce hypokalemia, Reduce or even stop using diuretics or digitalis preparations,A better clinical safety and compliance.