Anti-Gong Mi Suppository Treatment Chronic Cervicitis And Cervical Erosion(Syndrome Of Dampness-heat Pouring Downward) Research

ObjectiveThrough random,blind,contrasting clinic research of Anti - Gong Mi Suppository,preliminary evaluating the clinical effect and safety of Anti - Gong Mi Suppository treating chronic cervicitis and cervical erosion(syndrome of dampness-heat pouring downward).Methods1 Clinical data:The patients accorded with the diagnostic standard of cervical erosion of western medicine,and according to differentiation of syndromes in TCN it belonged to the type of damp invasion of lower energizer,64 cases were divided into treatment and control groups at random,the treatment group had 48 cases and control group had 16,both completed the study.For a consecutive 14-day drug treatment.Through statistical analysis,the age, scores of TCM Syndrome before treatment and classification of disease of the two groups are comparability.2 Medical usage:Given Anti - Gong Mi Suppository and matrine suppository respectively,two groups began to use it just three days after the menstrual cleaning.Suppository sophisticated inwards, was pushed into the vaginal depths gently,1suppository daily,14 days a course Moreover,the patients are asked to prohibit sex life. 3 Observation of efficacy and safety:To observe the size of cervical erosion surface,the degree of inflammation,TCM syndrome and sign,clop-clearing grade before and after the treatment.Blood routine,urine routine,liver function(ALT),kidney function(Bun, Cr),electrocardiogram test and vaginal discharge inspection are taken before and after treatment.TCT before treatment.4 Statistical methods:After treatment,we analyze the data.The Counting materials are examined with X~2,the measuring materials are examined with t-test and the grading materials are examined with Ridit-test.Results1 The total effective rate of the treatment group was 93.33%,While the control group was 83.33%,There was no significant difference between these two groups on the comprehensive efficacy(P＞0.05).2 Individual symptoms of TCM Syndrome indicators:There is not significantly different between the two groups(P＞0.05).The total effective rates of TCN Syndrome are 97.92%and 93.75%in control group and treatment group.3 Individual symptoms of TCM Syndrome indicators:Individual symptoms of TCM Syndrome(including the major symptoms and minor symptoms) have improved by different degrees.Through statistical analysis,the improvement of the major symptoms of TCM Syndrome is not significantly different between the two groups(P＞0.05).4 Local signs(gynecological examinations) effects:Both could significantly depress the integral about the size of cervical erosion surface,the degree of inflammation,clop-clearing grade after the treatment(P＜0.05).There was significant difference between the two groups on the area of cervical erosion and the TCM syndrome and sign efficacy(P＞0.05),The total effective rates of TCM Syndrome are 93.82%and 77.62%in control group and treatment group.It stated that the two groups had significant effect on the symptoms.There was no significant difference between the two groups after treatment(P＞0.05).5 Adverse reactions and side effects:no obvious adverse reactions and side effects in both groups during clinical study.All laboratory tests(Three conventional,liver and renal function,ECG)before and after the treatment had no treatment-related abnormalities.ConclusionObservations show that,through statistical analysis,Anti-Gong Mi Suppository could effectively treat chronic cervicitis and cervical erosion(syndrome of dampness-heat pouring downward), obviously improve erosion area,inflammation and the correlate symptoms,has no side effects.In a conclusion,Anti - Gong Mi Suppository also has a good foreground for clinic.