Polyinosinic Cells Point-injection Therapy In Coordination With Traditional Chinese Medicine Takes The Clinical Application Study Curing The Flat Wart

ObjectiveFlat Wart in clinical dermatology is a very common disease, is by the human papilloma virus(HPV)-induced skin hyperplasia, verruca plana for the cause,pathogenesis and recovery mechanism,the current clinically used to treat flat more warts methods[1],there are many to choose different types of drugs have anti-viral,immunomodulatory,anti-diagonalization, traditional Chinese and western medicine and local drug or physics,such as surgical treatment.Some patients to seek treatment for a number of treatment methods used,but the effect varied,it is difficult to cure.This makes the treatment of patients gradually lose confidence,causing great psychological pressure and even affect their normal life,work and social life.How to find effective and safe treatment of patients recovered completely,clinical work is an important topic,the author in August 2007 to November 2008 the use of cellular Polyinosinic internal point injection with Chinese medicine treatment of 101 cases of verruca plana,a certain effect,it is the systematic observation of therapy and to further test and demonstration of its efficacy and safety analysis of the advantages of this therapy and its mechanism, so as to provide objective clinical basis.Data and methodsPatients treated according to the sequence of random,open, the control method to 101 cases were randomly divided into two groups.Treatment group 51 cases,50 cases of the control group, treatment group Polyinosinic cell injection(Ryan Pharmaceutical Co.,Ltd.Xuzhou production) point injection, Each time 2milliliters,Every week 2 times,at the same time soup Quyou be decoction of Chinese medicine intake into the body, Every day medicinal preparation,Divides two clothing,the control group to give poly intramuscular injection muscle cells, Each time 2 milliliters,Every week 2 times,at the same time thymopeptide oral enteric-coated tablets(Changchun Overseas Pharmaceutical Group Co.,Ltd.),three pieces,one day of three times..And a week to observe the changes in skin lesions of all patients and written records,respectively,in the treatment of 4 weeks,8 weeks later to assess its efficacy,12 weeks after the follow-up observation of relapse cases.Results1.The total efficiency of the two groups:treatment group 51 cases,31 cases recovered,10 cases markedlyeffective,7cases improved,3 cases,total effective rate was 80.39%;50 cases of the control group,21 cases fully recovered,9 cases of effective,markedly effective in 10 cases,10 cases of null and void,with a total effective rate was 60.00%.After statistical analysis,the total effective rate were statistically significant difference(P＜0.05),prompted the efficiency of the treatment group there will always be better than the control group.2.Cure rate compared two groups:treatment group 51 cases,31 cases fully recovered,unless these 20 cases,the cure rate is 60.78%;50 cases of the control group,21 cases fully recovered, unless these 29 cases,the cure rate is 42.00%.After statistical analysis,the cure rate difference between the two groups was not significant(P＞0.05),prompt treatment group and control group cure rate considerable.3.Relapse rate compared twogroups:treatment group 51 cases, 50 cases of follow-up,1 loss,nine cases of recurrence,41 cases of non-recurrence,the recurrence rate was 18.00%;50 cases of the control group,49 cases of follow-up,1 loss,19 cases of recurrence,30 cases of non-recurrence,the recurrence rate was 38.78%.After statistical analysis,the relapse rate were significantly(P＜0.05),prompt treatment group than the control group,the relapse rate is more effective control.ConclusionComparison of the subjects taken in order to Polyinosinic point injection with cell Quyou soup internal medicine for the treatment group,together with the intramuscular injection of muscle cells thymopeptide oral enteric-coated tablets for the control group.,Respectively,were observed in the treatment of 4 weeks and 8 weeks after the effect of the case,12 weeks after the recurrence of the situation of the two groups were observed.Through statistical analysis,two groups of patients with significant cure rate,but higher than the total effective rate,the recurrence rate is lower than the control group. Description Polyinosinic cells with point-injection internal medicine can be effective treatment for verruca plana and verruca plana relapse control.