| Background Reduction of left ventricular function is a major risk factor for sudden death, so the evaluation of left ventricular function is particularly important. At present, more conventional echocardiography are applied to assess left ventricular function, but by the ultrasound beam angle, image quality and cardiac chamber deformation and many other factors, they may not precisely assess the left ventricular function. Tissue motion mitral annular displacement(TMAD) is a new technology which is based on speckle tracking technology. It uses semi-automatic method to track valve ring relative to the ventricular tip movement and quantitative analyse mitral annular motion parameters. TMAD technology is simple, intuitive, non-angle dependent.Objective To explore the clinical value of automated motion tracking of mitral annular displacement in assessing left ventricular systolic function in patients with dilated cardiomyopathy (DCM).Methods Left ventricular end-diastolic dimension (LVEDd), left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV) and left ventricular ejection fraction (LVEF) were measured with two-dimensional echocardiography in 30 patients with DCM and 20 healthy controls. The maximal displacement of six points of mitral annulus (Ds) was measured with TMAD, and the correlation between mean displacement (MDs) and LVEF was analyzed.Results Compared with healthy controls, LVEDd, LVEDV, LVESV increased significantly in the DCM patients (P<0.001), and LVEF decreased significantly (P<0.001). The displacement of six points of mitral annulus were lower in the DCM patients than those in the healthy controls (P<0.001). TMAD was positively correlated with Simpson's LVEF in the health controls and DCM patients(r=0.878,0.687, P<0.001).Conclusion TMAD can assess left ventricular systolic function in patients with DCM, and it could be a new method for clinical evaluating the left ventricular systolic function. |
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