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The Clinical Research Of Temozolomide Standard Treatment Of Early Postoperative Contrast To The Standard Program Plus Temozolomide Chemotherapy For Glioblastoma Multiforme Cell Tumor

Posted on:2011-07-01Degree:MasterType:Thesis
Country:ChinaCandidate:C H LingFull Text:PDF
GTID:2144360305958143Subject:Clinical Medicine
Abstract/Summary:PDF Full Text Request
Object:Evaluation efficacy and safety of temozolomide in contrast to the standard program of standard treatment plus early postoperative temozolomide chemotherapy for newly diagnosed glioblastoma multiforme tumorMethods:The 30 newly diagnosed glioblastoma pationts were divided into group A and B. A group of patients were assigned standard chemotherapy, B group were treated with both early chemotherapy and standard chemotherapy for 2 years, and observe the effect.Results:The total number of patients is 30, with A group of 15 persons and B group of 15 persons. The overall survival rate of A group was 73.33%, and the overall survival rate of B group was 80.00%; The progression-free survival rate of A group was 20.00%, and the progression-free survival rate of B group was 30.33%.Conclusion:The temozolomide standard treatment of early postoperative can not be significantly increased survival rate and Progression-free survival of the patients.
Keywords/Search Tags:temozolomide, glioblastoma, chemotherapy
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