The Clinical Observation Of Reflux Esophagitis Of Stagnation Of QI And Phlegm Retention With The Treatment Of Jiajian Banxia Houpu Tang

Objcetive:This study was designed to observe the clinical curative effect of treating of reflux disease(RE)with Jiajian Banxia Houpu Tang, and further to explore the mechanism in theory and clinical.Methods:1.Selected 60 cases of patients with RE, from out-patient of Medieine digest at a subsidiary of Shandong Province, Shandong University of Traditional Chinese Medieine Chinese medieine hospital in August 2008-August 2009 of cases.These cases are all diagnosed RE, according to the sequence of treatment, using random number table, which are divided into two groups, the treatment group(30cases)and the control group(30cases).Two groups have no significant difference in age, gender, disease duration and disease process(P>0.05), which is comparable.2.Control group is given oral omeprazole 20mg, bid;domperidone 10mg, morning and one in the evening, taking half an hour before a meal..Treatment group is given oral Jiajian Banxia Houpu Tang,one dose a day, boil with water to get 400ml, simmerit twice in morning and evening.One course of treatment for four weeks, a total of two courses taken.Westem medieine only oral control group, with the observation group.Two groups of patients to quit smoking during treatment were temperance, not into the greasy and irritating food, raise the head of the bed15-20cm, the attention of not eating before going to bed, do not use these drugs in addition to other drugs.Close observation during the clinical symptoms, one week out-Patient referral, recording symptoms, signs change, the treatment of endoscopic inspection before and after one meeting, in accordance with the domestic esophagitis grading criteria to determine the degree of inflammation level.During treatment were carried out security cheeks(general physical examination items, the three conventional laboratory tests, electrocardiogram, liver examination, possible adversere actions)and efficacy of observation.3.Statistical analysis methods:statistical software SPSS16.0 data for analysis. Information on the use of Level Ridit analysis, count data using X2 test, measurement data using t test.Results:1.Treatment group:5 cases of clinically cured,11 cases markedly effective, effective 9 cases,5 cases of invalid, total effective rate was 83.3%.Control group:6 cases of clinically cured, markedly effective in 10 cases,10 cases of effective and ineffective in 4 cases, total effective rate was 86.7%.Comparing the two groups have no significant difference(P>0.05).2.Before and after treatment were compared in patients with Chinese medicine symptom score were significantly different(P<0.05);the treatment group symptom score improvement of Chinese medicine is as well as the control group(P<0.05).3.The treatment group and control group are able to change the esophageal mucosal inflammation (P<0.05).Conclusion:This study suggests that Jiajian Banxia Houpu soup treatment of reflux esophagitis safe and effective herbs in improving clinical symptoms, elimination of esophageal mucosal inflammation are not less than the pure RE western medicine group, worthy of further study and expand the applications.