By Yiqi Yangyin And Qingli Huoxue-based Treatment Of Recurrent Membranous Nephropathy (Qi And Yin Deficiency And Heat Stasis Card) Clinical Observation

Objective:By observing the clinical effects of Yiqi Yangyin and Qingli Huoxue traditional chinese medicine combined with hormones, cytotoxic drugs and immunosuppressive therapy in the treatment of recurrent membranous nephropathy. to explor traditional Chinese and western medicine treatment of recurrent membranous nephropathy safety, effectiveness-and Part of the mechanism.Methods:A randomized,controlled clinical trial will be in line with the standard 49 cases of qualified subjects which divided into control group(he Western medicine treatment group) and treatment group(the combination of TCM with Western medicine treatment group) and Observation, evaluation of integrated effect of the two groups of patients, TCM syndrome score, urinary protein, plasma proteins, lipids and other targets. The measurement data were analyzed using two independent sample t test group。The measurement data were analyzed using the non-parametric test for which did not satisfy t test. Count data using chi-square (x 2) test, class rank and test with count data.Results:(1) The total effective rate comparison:The treatment group total effective rate was 65.4%,53.8% of the control group, treatment group was significantly better than the control group (P<0.05); (2) Comparison of TCM syndromes:Treatment The total effective rate was 78.2%, 57.7% of the control group, treatment group was significantly better than the control group (P<0.05); (3) Compare by two groups of one selves:After treatment, serum albumin increased, decreased urine protein, blood lipid decreased coagulation PT, APTT extension (P all<0.05); between the two groups:the treatment group significantly better than the control group (P<0.05); (4) Hormones and cell malicious medicine due to the incidence of side effect is reduced for treatment groupConclusion:Yiqi Yangyin and Qingli Huoxue Treatment RMN (Qi and Yin deficiency and heat stasis certificate) is safe and effective, and can reduce urinary protein, blood lipids, and elevated plasma protein, mainly to improve the clinical symptoms, and reduce hormones, immunosuppressant drugs due to side effects. That party may be related to enhance immunity, anti-inflammatory, lipid, improve whole body and local micro- cycle, and improve the vascular permeability, immune complex clearance such as glomerular basement membrane. So it is worth further study for us.