Study On Risk Factors Of Hypertension And Prehypertension Among Entry-Exit People

Objective The present study was conducted to investigate the current situation and risk factors of hypertension and prehypertension., and to provide the scientific evidence for disease control and prevention against hypertension.Methods Height, weight and blood pressure were measured, and fasting plasma blood, plasma lipid, blood urea nitrogen (BUN), creatine (CREA), uric acid (UA) and other biochemical parameters were examined for 4 237 entry-exit people in Kunshan city, from January 1,2008 to October,31,2008. The relationships between hypertension, prehypertension and various risk factors were analyzed, multivariate logistic analysis, was used to analyze the association between BUN,CREA and UA levels and hypertension and prehypertension.Results Among 4 237 subjects, there were 1548 subjects with hypertension, and the prevalence of hypertension was 36.43%.The age, male ratio, BMI, SBP, DBP were all higher in the hypertensives than that in prehypertensives, the age, male ratio, BMI, SBP, DBP were all.higher in the prehypertensives than that in normotensives,TC,TG,LDL-C,HDL-C and FBG levels were all higher in the hypertensives than that in prehypertensives, TC,TG,LDL-C,HDL-C and FBG levels were all higher in the prehypertensives than that in normotensivesBUN(4.7 vs.4.6),CREA(80.0 vs.76.3)and UA(351.0 vs.317.5)were all higher in the hypertensives than that in prehypertensives, BUN (4.7 vs.4.6),CREA (80.0 vs. 76.3) and UA (351.0 vs.317.5) were all higher in the prehypertensives than that in normotensives(4.6 vs.4.4; 76.3 vs.67.0; 317.5 vs.256.0).The subjects were evenly divided into 3 groups according to tertiles of UA levels, compared with the those with lowest tertile of UA level, the ORs of hypertension and prehypertension associated with the second and third tertile of UA level were significant no matter whether adjusting for multivariate or not, the ORs of hypertension and prehypertension increased with elevated UA. The risk of hypertension and prehypertension in the subjects with third tertile of UA level were 2.42 andl.56 folds compared with those with the lowest tertile of UA level.Conclusion:Age, male ratio, overweight, hyperglycemia and hyperlipemia were associated with hypertension and prehypertension; elevated UA was associated with hypertension and prehypertension.