Comparison Of SC And PSV Used In Difficult Weaning Patient: A Randomized Prospective Study

Objective:To compare the variation on hemodynamics and respiratory mechanics of Smart Care/PS and PSV used in difficult weaning patients, in order to evaluate if the Smart Care/PS weaning is superior to PSV weaning. Method:When fifty-seven difficult weaning patients were fitted to the weaning condition, they were randomized into 2 groups:weaning with Smart Care/PS (SC group, n=15)or with pressure support ventilation(PSV group, n=14). The basic ventilation mode was SIMV+PSV before weaning. The two groups used Smart Care/PS and PSV respectively. Parameters of pulmonary mechanics and hemodynamics were measured at 5 min,15 min,30 min,1h and 2h after weaning. The collecting dates were analyzed by repeated measurement analysis of variance. Results:(1) The f,Vt,P0.1,NIF and HR had no significant difference between the two weaning modes (P>0.05); but they had difference at each times (P<0.05). (2) The PetCO2,C,R,MAP and CI had no significant difference between the two weaning modes (P>0.05) and at each times (P>0.05). Conclusion:For those difficult-wean patients caused by postoperative CNS disease and pulmonary infection, Smart Care/PS can take the place of PSV, simulate the doctor judging and dealing with pressure support level according to the patients condition and can be used to automated weaning.