Study On Quality Of Life Of Patients With The Benign Prostate Hyperplasia And Its Influencing Factors

Objective The purpose of the study was to compare the differences in the quality of life between benign prostatic hyperplasia (BPH) patients and community healthy male residents, analyze its main influencing factors, and explore the correlation of the state anxiety, medical coping modes with the quality of life, thus providing the evidence for carrying out health promotion tasks for BPH patients both in the community and the clinic.Methods During April 2010 to January 2011, by using convenience sampling method, 170 patients with BPH (waiting for Transurethral Resection of Prostate) in seven hospitals'urology surgery wards in one city of anhui province were interviewed. The measuring instruments included quality of life by Medical Outcomes Study 36-Item Short-Form Health Survey scale ( SF-36), state anxiety inventory, medical coping modes questionnaire, and international prostate symptom score (IPSS) , meanwhile, SF- 36 was also applied to investigate the quality of life among 121 community healthy male residents. One sample t-test was used to compare the score of state anxiety between the BPH patients with the norm obtained from the normal males, and the score of coping modes between BPH patients with the norm gained from the clinical patients. Mann–Whitney U test was applied for comparing the differences in quality of life between BPH patients and community healthy male residents. Pearson correlation analysis was used to analyze the relationships among the state anxiety, medical coping modes, and the quality of life. The single factor analysis was applied to analyze the potential influencing factors of the quality of life among BPH patients, and multiple stepwise regression analysis was further made to screen out the main influencing factors based on the previous analysis.Results 162 valid questionnaires from BPH patients and 113 from community residents were included for this analysis. There was no statistical difference in the scores of state anxiety between the BPH patients and the healthy males'norm ( BPH patients: 38.06±11.99, norm: 39.71±8.89, P > 0.05). There was also no significant difference in the dimention of "facing" coping mode between the BPH patients and general clinical patients (BPH patients 19.69±4.27, norm 19.48±3.81, P > 0.05), while the BPH patients had a relatively higher score than the norm from clinical patients in the dimention of"avoiding"coping mode (BPH patients 16.04±2.18, norm 14.44±2.97, P < 0.01), and the BPH patients had a lower score than the norm from clinical patients in the dimention of " yielding " coping mode (BPH patients 7.98±2.82, norm 8.81±3.17, P < 0.01).The correlation between the state anxiety and the coping modes of "facing"and"avoiding" was not statistically significant (P > 0.05), while the state anxiety had a positive correlation with "yielding" coping mode (r = 0.515, P < 0.01). The quality of life of BPH patients was significantly lower than community male residents (BPH patients 60.91±17.37,the community residents 81.17±11.94, P < 0.01). The state anxiety negatively correlated with the total score of quality of life and some sub-dimentions, namely, physical functioning, role limitations due to physical health, general health, Energy, social functioning, role limitations due to emotional problems, emotional well being, physical health, and mental health (r = - 0.076 ~ - 0.519, P < 0.01), while there was no statistical correlation between the state anxiety with the"pain"dimention of quality of life (P > 0.05). The coping modes of "facing","avoiding" was neither statistically correlated with the total score of quality of life, nor its each dimension (P > 0.05), while the " yielding " coping mode negatively correlated with the total score of quality of life and its all dimensions (r = - 0.195 ~ - 0.521, P < 0.05). The single factor analysis suggested that the age,education, marital status, and the duration of the disease were possible influencing factors of the quality of life with statistical significance(P < 0.05). Multiple stepwise regression analysis indicated that"yielding"and"facing"coping modes, state anxiety, international prostate symptom score were the main influencing factors of the quality of life among BPH patients.Conclusion The quality of life of BPH patients was significantly lower than the community healthy male residents. Comparing with the general clinical patients, the BPH patients also used the same "facing" coping strategy, and more inclined to use "avoiding" coping modes, and less use of "yielding" coping style. Among the influencing factors of the quality of life in BPH patients, emotional factors were more important than the physical factors, and the influences of emotional state and coping modes transcended that of disease symptoms. Improving the quality of life of BPH patients should begin with developing effective coping modes, highlighting the adjustment from psychologically adverse emotional reactions, and attaching importance to the emotional support from the patients′family members.