Therapeutic Effects Of Hole-treatment Method Based On Menstrual Cycle To Patients With Cyclomastopathy With Incoordination Between Chong And Ren Meridians

Objective:Therapeutic effects of hole-treatment method based on menstrual cycle to patients compared with regulation of chong and ren meridians in treating cyclomastopathy through studying clinical trial are observed in this subject, in order to demonstrate the validity of hole-treatment method based on menstrual cycle to patients in treating cyclomastopathy with incoordination between chong and ren meridians.Method:Chose 40 cyclomastopathy patients with incoordination between chong and ren meridians, and randomize them equally into a treatment group (including 20 patients) and a control group (including 20 patients). The treatment group received the treatment of hole-treatment method based on menstrual cycle to patients and used medication during four periods, relatively menstrual period, postmenstrual, intermenstruum and premenstruum. The treatment of the menstrual period was promoting coronary circulation, in which drainage aid was put first and assisted with uterus and meridians warming. The treatment of the postmenstrual (about 7 days after menstruation) was nourishing the blood and Yin, in which way the emptiness of flush vessel was filled. The treatment of the intermenstruum (about 14 days after menstruation) was nourishing Yin and strengthening Yang, in which way the nephron was vigorous, the kidney-yin was enriched, and thoroughfare and conception vessels were unobstructed. The treatment of the premenstruum (about 7 days before menstruation) was soothing the liver and strengthening yang. The control group received the treatment of regulation of chong and ren meridians and took Er-Xian decoction and decoction of four drugs properly. The two groups received the corresponding treatment for 3 continuous months. After treatment, the changes of both clinical syndromes in traditional Chinese medicine, such as quality and size of lump in breast, pain of udder and the degree of menorrhalgia, and basal body temperature were observed. Meanwhile, levels of esteadiol, luteining hormone, progesterone and prolactin were compared with those before the treatment.Results:1. After treatment, treatment group (T), compared with comparison group (C), can performs slightly better in effectively controlling the quality of target mass, reducing the size of target mass, relieving the twinge of breast, algomenorrhea and some other syndromes of clinical Chinese medicine (P>0.05).2. After treatment, there is a slight increase of the levels of progesterone (P) and luteinizing hormone (LH) and decrease of the level of and estradiol (E2) and prolactin (PRL) but with no disctinctive difference (P>0.05).3. The change of the level of E2, LH, P and PRL has no statistical significance between the two group after treatment(P>0.05).4. The ratio of E2/P drops and has significant difference with both before,but no statistical differentce with C (P<0.05).5. T after treatment can obviously shorten the time needed for temperature increase, lengthen the lasting of High Temperature Phase and lessen the fluctuation of High Temperature Phase, with a distinctive difference from before treatment (P<0.05).6. C after treatment can only slightly shorten the time needed for temperature increase, slightly lengthen the lasting of High Temperature Phase and lessen the fluctuation of High Temperature Phase, with no distinctive difference from before treatment (P>0.05).7. Comparing the temperature change of both groups after treatment, T precedes C in all the following aspects:shortening the time of temperature increase, keeping the time of High Temperature Phase and controlling the fluctuation of High Temperature Phase; it has no statistical difference, though (P>0.05).Conclusion:In treating cyclomastopathy with incoordination between chong and ren meridians, compared with regulation of chong and ren meridians, hole-treatment method based on menstrual cycle to patients can controlle the quality of target mass, reduce the size of lump, alleviate the pain of udder and menorrhalgia slightly more effectively, and has an a slight advantage in improving the levels of P and LH, and lowering the ratio of E2, PRL and E2/P. Moreover hole-treatment method based on menstrual cycle to patients can shorten the time of temperature rising, keep the time of high temperature and control the fluctuation of body temperature under high temperature better than regulation of chong and ren meridians, which indicates indirectly that hole-treatment method based on menstrual cycle to patients is better in optimizing ovarianfunction than regulation of chong and ren meridians. This clinical trial research demonstrates that hole-treatment method based on menstrual cycle to patients can be used to treat cyclomastopathy with incoordination between chong and ren meridians, and its ideas are accorded with the fundamental principle of traditional Chinese medicine.