Study On Material Foundation Of Anti-inflammatory Compound Capsule

Anti-inflammatory compound capsule is a Chinese traditional compounds medicine which is composed with Dianthus superbus, Achyranthes, Poria, Alisma, fleas off, white silkworm, Common Yam Rhizome.It can cure anti-inflammatory obviously. Some doctors of our hospital use it and the therapeutic efficacy is reliable. The medicines which compose the prescription have complicated constituents, such as flavonoids,saponins, proteins, acids, polysaccharides.We research the chemical constitutions of the prescription for further purpose to look into material basis of phaemacotical activities in the Anti-inflammatory compound capsule.The subject in the pharmacological experiments, under the guidance of the anti-inflammatory compound capsules in different parts of solvent extraction, chemical composition of active screening, and chemical composition of its anti-inflammatory effect has been systematically studied.The pharmacological experimental research has indicated that ethyl acetate extracts of Anti-inflammatory compound capsule restrain inflammation obviously. Then we have taken out a series of studies on the chemical constituents of Anti-inflammatory compound capsule.8 monomers have been isolated on column chromatography of silica gel from ethyl acetate extract and 5 monomers structures of them have been identified as 2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethy1-1,3 (2H,9bH)-Dibenzofurandione (Ⅰ), luteolin (Ⅱ),β-Ecdysone (Ⅲ),β-Sitosterol (Ⅳ), Daucosterol (Ⅴ).Finally,the composition of compound anti-inflammatory medicine capsules chemical constituents and pharmacological effects are reviewed.Theme words:Anti-inflammatory compound capsule; material foundation; structure identification...