Purpose:Patients with chronic eczema by pruritus score and serum before and after treatment of histamine and leukotriene B4 level changes, Observed cupping method of treatment of chronic eczema of the clinical efficacy and mechanism, and the application.Methods:The clinical diagnosis of 72 patients with chronic eczema, Randomly assigned to oral antihistamines plus cupping group, oral antihistamine group, cupping group. Which cupping plus 24 cases of oral antihistamines, Given cupping method, At the same time to oral antihistamines loratadine tablets 5mg, Cupping therapy every other day 1, 10 times for one course, Oral loratadine tablets in a day, A course of 20 days; Antihistamine group of 24 patients,With oral antihistamine loratadine tablets in 5mg,1 tablet per day, A course of 20 days; Cupping the 24 cases, Given cupping method,1 treatment every other day,10 times as one course of treatment. After a course of clinical efficacy, Before and after treatment and serum levels of histamine and leukotriene B4 levels. After treatment, follow-up one month to observe the recurrence of itching. Results:1. Efficacy data observed before and after treatment showed the two groups:Cupping set, anti-histamine group, cupping plus antihistamine group, the total effective rate was 91.67%,87.50%,95.83%, Comparison of three treatment methods before and after treatment have a significant effect (p<0.05). Cupping treatment group and anti-histamine group and thorn resistant group similar effect, no significant difference between the three (p>0.05).2. Experimental results show that:All three methods can make eczema patients is histamine, leukotriene B4 levels decreased, and both have significant (p<0.05). Comparison between the three groups were statistically different (p<0.05), cupping group is less than the antihistamine group and thorn resistant group, anti-anti-histamine group and thorn was no significant difference between groups.3.Cupping group and Acupuncture and anti-relapse treatment of eczema group was significantly lower than antihistamine group4. Three groups according to the provisions of medication, the medication process no obvious adverse reactions.Conclusion:(1) Cupping law degree in relieving eczema itch no difference between the efficacy and antihistamines (2) Cupping method can reduce the eczema itch mediators (histamine, leukotriene B4) level, but significantly better than antihistamines.(3) Cupping Treatment of eczema itching relapse rates were significantly lower than the antihistamine group, significant long-term efficacy, and the method is simple, easy to be accepted and effective, side effects, clinical worth promoting.(4) Histamine levels in patients with body eczema, leukotriene B4 levels were significantly higher than the normal, Itching caused by eczema itch that the media and in vivo histamine, leukotriene B4 on.(5) Cupping method can significantly alleviate the degree of eczema itching, and antihistamines without distinction, but reduced itch mediators (histamine, leukotriene B4) level was not as good as antihistamines, further evidence of the cause of eczema Itching of the media must not limited to these two, so the mechanism of the mechanism of eczema remains to be further explored. |