Advocating that the deficiency of Qi and blood,the interaction of both clear and turbid Qi,and the accumulation of phlegm are improtant pathogeneses for the senile hypertension,this arcticle suggests the subsequent treating approaches for the senile hypertension-invagorate Qi to nortish blood,elevate clear Qi to lower turbid Qi and remove blood stasis to get rid of phlegm.Using above for our prescription principle,based on clinical experences,we made this hypotensor桪ing Xuan Jiang Ya Mixture.The clinical research indicates that Ding Xuan Jiang Ya Mixture can not only improve the symptoms of the senile patients clinically but also not notably reduce blood pressure,simultaneously promoting blood-fat, blood-sugar and blood-rheology. It can especially lower ET,AT-II and ETICGRP,heiglitening CORP in blood plasm. The total efficiency for improvement is 88.9%; The total efficiency for reducing blood pressure is 86.67%. This is preferable to the control group in Qing Xuan Jiang Ya Pian.In terms of experimental studies; Ding Xuan Jiang Ya Mixture can not only lower the blood pressure of the mice with spontaneous hypertension but also lower the ET,AT-II,TXA2, and ETICGRP, thus elevating CORP in blood spasm, It is also capable of lowering SOD and MDA, and of antioxidents,To sum up,the advocated pathoqenesis and treating method in article are consistent with clinical experiences, the hypotensor on the basis of invagorating Qi to nourish the blood, elevating clear Qi to Lower turbid Qi, and the like is indeed efficacious for the disease and the improvement to relevant symptoms is attributable to its comprehensive effects. |