The Blood-brain Natriuretic Peptide Levels And Cardiac Function And Prognosis After Acute Myocardial Infarction Analysis

Objective To evaluate the value of B-type natriuretic peptide(BNP) in estimating risk stratification in patients with acute myocardial infarction(AMI) and to determine the relationship between BNP and adverse cardiac events after AMI.Method The plasma concentrations of BNP were measured with Triage BNP test at 7±3 days after AMI in patients and heathy controls. Patiens were followed up at 12 months. The main outcome measure was mortality at one year.Result The plasma BNP concentrations in patients with AMI were much higher than those in the health control people(550.4±789.7pg/ml versus 26.4±27.4pg/ml, P<0.001). There were significant different between the different ventricular dysfunction. Weather or not percutaneous intervention, The development of any of the clinical end points occurred more frequently in patients with a higher BNP count.Conclusion The results of the present study confirm that the elevated BNP count related to the risk stratification and prognosis in patients with AMI. Elevations in BNP count are associated with a higher incidence of new CHF and adverse clinical outcomes after AMI. Plasma BNP concentrations were correlated with LVEF in patients with AMI. After PCI, the plasma BNP were significantly decreased in one week with AMI and cardiac death were decreased in 12th month. It could serve as a stong predictor for the subsequent development of poor outcomes in AMI patients.