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Polygala Medicinal Herbs And Their Processed Products Of The Quality Of Research

Posted on:2009-12-08Degree:MasterType:Thesis
Country:ChinaCandidate:W J ZhangFull Text:PDF
GTID:2204360242488371Subject:Pharmacy
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To establish the evaluating index and method of principal component for quality control in Polygala tenuifolia Willd,Our article analyzed the wild Polygala tenuifolia,cultivated Polygala tenuifolia,commercial PolygaIa tenuifolia and the Processed Radix Polygalae by HPLC fingerprint,Statistica and content mensuration.The results are almost consistent with chronically using.Then,seven ranks of Polygala tenuifolia samples from Ping Yao of Shanxi were analyzed by HPLC with gradient elution. Clustering method and Principal Component Analysis(PCA)were processed according to the peak area.We owned the evaluating equation.This method confirms the conclusion that Polygala tenuifolia has many effective components,demonstrating that it can be used for the quality evaluation and development of new resource of POlygala tenuifolia.Besides,one orthogonal test was employed to determine the effects of the three factors.The content of senegenin(C30H45O6Cl)and glycyrrhizic acid(C42H62O16)were determined by HPLC.The best decoction techinics was satifued with some conditions as follows:Adding 100mL water to Glycytthizae,its baking time was 30min,baking three times.The best preparative technics was satisfied with some conditions as follows:Adding 2.5 multiple Radix Glycytthizae-water to Radix Polygalae,its baking time was 90min.baking temperature was 140℃,and drying temperature was 100℃. This research is meaningful to standardization of stir-bake with Radix Glycytthizae on Radix Polygalae.Furthermore,we had constituted a special standard for Processed Radix Polygalae.HPLC fingerprint and Coefficient of Variance were used to analysis Radix Polygalae and Processed Radix Polygalae.The result showed that the Processed Radix Polygalae was the most variation.
Keywords/Search Tags:Radix Polygalae, Processed Radix Polygalae, Quality research, stir-bake technology, Statistical analysis
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