Citrus Aurantium Processing Technology And Quality Standards

Purpose:Fructus aurantii immaturus is the dried and immature fruit, which belongs to Citrus aurantium L.Or Citrus sinensis Osbeck has the strong effectiveness on promoting gas and eliminate sputum.Fructus aurantii immaturus processed by stir-baking with bran is only processed product in Pharmacopoeia of the people republic of China.But its procedure is indefinite.So the topic is to optimize the procedure of Fructus aurantii immaturus, compare the effect on stomach and small intestine of before and after procedure,establish the quality criteria of Fructus aurantii immaturus's processed product.Material and method:Materia:Fructus aurantii immaturus purchased from Jiangxi province,identify by ZHAI Yan-jun, Professor who belongs to staff room of the identification of chinese materia medica which belongs to Liaoning University of Traditional Chinese Medicine, is the real one.Method:1. The best process of Fructus aurantii immaturus'decoction pieces were optimized by L9(34) orthogonal design experiment.2. Serving the Synephrine and Flavone as the index,acting the quantity of bran,the temperature of procedure and the time of procedure as factor of investigation,the procedure was optimazed by orthogonal design.3. The mouses were feeding service by extract of each fraction of Fructus aurantii immaturus and its processed product and injecting with some kinds of drug. The effective on invigorating the spleen was compared by determining gastric emptying and facilitation of bowel.4.Serving the Synephrine and Flavone as the index,the quality criteria of Fructus aurantii immaturus and its processed product was established .The moisture content,ash content and extractive of its processed product of ten habitats were determined. Results:1.The optimal procedure was that the quantity of water was 1:1 and until the water were assimilate take it cut it into middle pieces . Dry it with the temperature was 60 and time was 12 hours.2. The optimal procedure was that the temperature was 180, time was 60 seconds and the quantity of bran was 100:5,optimized by orthogonal design.3. Each kinds of drug had an effective on depressing down gastric emptying and facilitation of bowel,which has something difficult in itself.4. The technology of Synephrine and Flavone consistented with relative regulation.The content of Synephrine was tentatively set on more than 0. 2 %,the content of Flavone was more than 5 %.Conclusion:1.The optimal procedure of processing decoction pieces is determined.2. The optimal procedure of processing drugs is determined.3. Fructus aurantii immaturus and its processed product had an effective on revert the gastric emptying and facilitation of bowel,which has something difficult in itself.4. The moisture content,ash content and extractive of Fructus aurantii immaturus's processed product of ten districts were determined and the quality criteria of its processed product is stable and feasible.