Observation Of The Clinical Effect For Treatment Of Premenopausal Syndrome With Yang Deficiency Of Spleen And Kidney

[Purpose]Observe the difference of the clinical effect and possible mechanism between acupuncture with traditional Chinese medicine and simple Chinese medicine in treating premenopausal syndrome with yang deficiency of spleen and kidney to find the best therapy for clinical application and provide a scientific basis.[Method]In this study,60 cases of premenopausal syndrome with yang deficiency of spleen and kidney (according to modified Kupperman score standard) were digital randomly divided into 2 groups, including acupuncture with traditional Chinese medicine group of 30 patients, simple Chinese medicine group of 30 patients. acupuncture with traditional Chinese medicine group:we choose the points below:zhi san zhen points, bai hui point, nei guan point, shen men point, guan yuan point, zi gong point, zu san li point, san yin jiao point, tai xi point, tai chong point and so on, moxibustion on shen que point, meanwhile taking the traditional Chinese medicine(same with the simple Chinese medicine group). The simple chinese medicine group:using the specified formular for premenopausal syndrome with yang deficiency of spleen and kidney in Gynaecology department in JiangSu provincal hospital of TCM,includes:gou teng 15g(boiled last), dan pi 10g, dan shen 10g, shan yu rou 10g, bie jia 10g(boiled first), huai shan yao lOg shu di huang 10g, sheng di huang 10g, chuan duan 10g, sang ji sheng 10g, gou qi zi 10g, du zhong 10g, fu ling 10g, lian zi xin 3g, xian ling pi 10g, tai zi shen 10g, ye jiao teng 15g, shou wu 10g, dong sang ye 6g, he huan pi 10g, tu si zi 10g, hong hua 6g, mei gui hua 6g.all of them boiled into decoction for the patients. acupuncture with Chinese medicine group:using the common acupuncture therapy on the points mentioned above with moxibustion on shen que point,3 times a week. Meanwhile let the patients to take one decoction everyday,2 times a day. Four weeks for a course; the simple Chinese medicine group:daily take traditional chinese medicine decoction, two times a day, also four weeks for a course. according to the modified Kupperman score standard to judge the improvement of clinical effect and change of hormones levels before and after the two different kinds of therapy methods respectively.[Result]Analysis according to the modified Kupperman score standard,two groups of treatment are effective, and the score is better than that before the treatment. But the comparison of curative effecbetween two groups shows that acupuncture with Chinese medicine treatment result is obviously better than the curative effect of Chinese medicine group.(P<0.01), the clinical symptoms improved obviously comparing with the symptoms before treatment.But comparing between the two groups, before and after the treatment,the hormone levels have no statistically significant.[Conclusion]Acupuncture with Chinese medicine and the Chinese medicine group do all have the curative effect in treating premenopausal syndrome with yang deficiency of spleen and kidney. But for the acupuncture with Chinese medicine group, the clinical symptoms improved significantly better than simple chinese medicine group, compared with the symptoms before treatment,after the treatment,the clinical symptoms improved more obvious.It can deserve the widely clinical application.