Clinical Research And Discussion Of Treating E₂,PRL And Rheology Of Blood Of Myoma Of Uterus On Damp-Heat Blood-Stasis Retention Type With Xiao Ji Power

Objective;To observe the effect of Xiao Ji powder in treating the clinical symptonms,physical,sex hormones(E2,P), rheology of blood of myoma of uterus and to explore its mechanism,are based on clinical study.Methods:Clinical Researth:52 patients due to the study typs were divided into tow groups randomly,30 patients are settled as experimental group,who are treated with Xiao Ji powder;22patiens are settled as control group,who are treated with capsule of Gong Liu Xiao.Before and after treatment,the clinical symptoms,physical sign,rhelogy of blood, E2,P are observea.Analyze the results with statistical methods, comprehensive determine its clinical efffects.Results:The total efficiency rate of the treatment group is 90%; the control group,22 cases, and the total efficiency rate of control grop is 78%. The total therapeutic effect of two sets has no significant deviation by the statisitical treatment(P>0.05).Symptomatic efficacy of Traditional Chinese Medicine:the total effective rate of the treatment group and control group were 93% and 78%,compared the two groups were significant deviation (P<0.05). Myoma of uterus effect: the total effective rate of the treatment group and control group were 90% and 73%, both groups showed no significant deviation(P>0.05). Uterine volume:two groups of patients before and after treatment can reduce the size of the uterus, the treatment group (P<0.01), the control group (P<0.05), before and after treatment between the two groups no significant difference between treatment (P>0.05).Tumor area:two groups of patients had fibroids shrink after treatment (P<0.05), between the two groups showed no significant difference (P>0.05). Syndromes integration:before and after treatment were significantly different (P<0.01), the control group before and after treatment showed no significant difference (P>0.05), between the two groups are significantly different (P<0.05), that treatment group than the control group. E2, PRL:before and after treatment, E2, PRL had decreased, there was significant difference (P<0.05), control group, no significant decrease after treatment, no significant difference (P>0.05), between the two groups were two groups of patients There was a significant difference (P<0.05).Rheology of blood:governance before and after treatment with high shear relative viscosity, erythrocyte aggregation index, low-shear relative viscosity were significantly improved (P<0.05), in which the value of plasma viscosity before and after treatment group improved more significantly (P<0.01); control group before and after the high shear relative viscosity, low shear relative viscosity were not improved (P>0.05), plasma viscosity, erythrocyte aggregation index had improved after treatment (P<0.05); high shear relative viscosity, erythrocyte aggregation index, low-shear relative viscosity, plasma viscosity between the two groups showed no significant difference (P>0.05).Conclusion:Xiao Ji powder which is a secure and effective recipe in teating myoma of uterus.The demonstrated change of the clinical symotom and physical sign, and decline rheology of blood, sex hormones (E2, PRL),and its mechanism underlies in regulating the body's hormone levels and it declining the blood rheology to achieve the purpose of treatment, with the favourable security.