The Radiofrequency Ablation Therapy For Phc

[Objectives]The purpose of this study was to summarize the characteristics of Primary Hepatic Carcinoma (PHC) and the development and strategies of Radiofrequency Ablation. It also compared the effect of Radiofrequency Ablation (RFA) and surgical resection as the treatment of Primary Hepatic Carcinoma.[Methods]The clinical data of 61 cases with small primary liver carcinoma(≤5 cm) who were treated from January 1st,2004 to December 31st,2007 was analyzed retrospectively. Twenty-eight cases of them had received RFA treatment while the others had gotten surgery. All cases received the conservative treatment after admission. Different operation methods were taken according to the general condition of patients, the size and location of the tumor and the different degree of cirrhosis of the liver. As to RFA treatment, the patients were treated in ultrasound-guided percutaneous way under local anesthesia. Ultrasound intraoperative monitoring was used to ensure that inactivated range covers the tumors. We analyzed the overall 1-year,3-year and 5-year survival rates and the complications of the two groups. SPSS 17.0 was used to analyze the data. Survival probability was estimated by the Kaplan-Meier method, differences between survival curves were evaluated by the Log-Rank test.[Results]1. All patients were good in anesthesia during operation, there were no anesthesia related complications. All the patients had fever or pain of different degree. Complications in the surgical resection group were as follows:hydrothorax(two), seroperitoneum(one).gastrointestinal bleeding(one), intraabdominal hemorrhage(one).nausea and vomiting (five).Complications in the RFA group were:hydrothorax(one).nausea and vomiting(one).2. The 1-,3-and 5-year overall cumulative survival rates after radiofrequency ablation and surgical resection were 96.3%,67.1%,52.6% and 96.9%,71.7%,58.6% respectively. The difference between the two survival curves was not statistically significant (P>0.05).[Conclusion]1. Radiofrequency ablation, with similar curative effect to surgical resection, was a safer and more satisfactory treatment for small liver carcinoma(≤5 cm), which can be selected to small liver carcinoma as one of the treatments.2. The incidence of complications for RFA was lower than the surgery.