The Clinical Observation About The Treatment Of Nonerosive Reflux Disease Syndrome Of Incoordination Between Liver And Stomach With XingQi TongJiang Tablet

Objective: Observe to do so leads down to nonerosive reflux disease, syndrome of incoordination between liver and stomach, the clinical effect of XingQi TongJiang tablet. Through the research of treatment and clinical about nonerosive reflux disease to explore new methods.Methods:Nerd in the diagnosis and syndrome of incoordinat-ion between liver and stomach credit standards of syndrome differentiation. First anxiety self-assessment rating scale and esophageal pressure measuring,45 patients were included in. Adopt draw law randomly divided into two groups. The treatment group (proprietary Chinese medicine group) 24) and the control group (western medicine group) 21 patients. In both groups respectively from the extraction of 10 routine 24 hours esophageal pH monitoring. Oral treatment group to XingQi TongJiang tablet,4 piece, tid; The control group to ray Bella thiazole oral,20mg, qd. Both groups treatment 8 weeks. After treatment, judge therapeutic effect.Results:(1)Clinical curative effect:17 cases in treatment group got clinical cure,5 cases powerfully, the total is 91.67% significant efficiency,1 cases failure in the effective; the total effective 95.83%. The control group got clinical cure in 7 cases,7 cases powerfully, total significant efficiency 66.67%, effective 1 cases failure; the total effective 71.43%, two groups of comparisons total effectiveness greup, P<0.05. The treatment group before treatment for syndromes integral 10.92±2.18 points. Treatment for 8 week 1.04±2.23 points. Syndromes integral more before treatment for significantly less, symptoms improved, P<0.01. Before treatment the control group syndromes integral 11.14±1.96 points, after treatment 2.86±3.52 points. There were significant differences before and after treatment,P<0.01. After treatment, the two groups of traditional Chinese medical syndrome integral compare different significantly, P< 0.05. The curative effect of treatment group was better than control. (2) 24 hours esophageal pH monitoring improvement:Observe 20 cases of 10 cases, the treatment group. DeMeester score before treatment 21.20±11.78 points. After treatment 7.70±1.95 points. Controls 10 cases, DeMeester score before treatment 20.90±8.90 points. After treatment 6.90±1.92 points. DeMeester score before treatment after treatment were no statistically significant difference between the two groups of comparisons gender, P> 0.05. (3) Esophageal pressure measuring improvement:45 cases were observed, the treatment group 24. LESP before treatment 8.96±2.98mmHg, after treatment 13.42±2.41mmHg. LESP improved obviously, P<0.01.21 cases of control group, LESP before treatment 8.48±2.92 mmHg, after treatment 9.52±3.14mmHg, LESP no obvious improvement,P> 0.05. After treatment, the two groups LESP comparative differences have significant, P<0.05.(4) After treatment, the ratings improvement SAS:Treatment group, before treatment 47.50±7.49 points. After treatment 34.25±7.89 points. Anxiety obviously improve P< 0.01. Control group, before treatment 47.48±7.91 points. After treatment 43.19±7.80 points. Anxiety no obvious improvement, P> 0.05. After treatment, the two groups of SAS score comparative differences have significant, P< 0.05.Conclusion: syndrome of incoordination between liver and stomach of NERD can be effectively treated by XingQi TongJiang tablet, the way of soothing the liver and harmonizing the stomach, promoting the circulation of qi and descend the adverse Qi.