| Objective: Infantile diarrhea is a group of diseases caused by a variety ofpathogens and factors, with the characteristic of increasing in stool frequencyand changing in stool traits,which is one of the most frequent diseases in thechildhood, as well as an important global public health problem today. In theworld there are1.5to2million children die from diseases whose incidencerate is second only to respiratory infections, or complications related withdiarrhea every year. China is a developing country. She has relatively weakeconomic foundation and a vast territory and large population, and imbalancesbetween different regions. Although in the past half-century the nation havedone a lot of work with environment, diet and water, diarrhea is still a groupof diseases that affects the lives and production of the people most commonly.Because it often has the long course of disease, recurs, and is difficult torecover, it is likely to result in malnutrition and hypoimmunity and to greatlyaffects the health and growth of the children. Modern medicine adoptsmaintaining the balance of Water-Electrolyte and acid and alkali, supportingtreatment. About infantile diarrheal diseases there is no special therapeuticmeasure to deal with. Using traditional Chinese medicine which has manypriorities, including overall efficacy, little side effect and so on, show theadvantages and characteristics of Chinese medicine and achieved a betterclinical effect. There are classified into five types the basis of symptoms: foodtype, cold type, damp-heat type, deficiency of the spleen and the spleen andkidney yang. The most common type is damp-heat diarrhea, so the most pointfor the research is gegenqinlian decoction. To small formation of hydrochloricacid alkali as a control group, an objective evaluation of gegenqinlianmodified decoction treats infantile diarrhea (damp-heat) clinical effective.Methods: Sixty enrolled patients were randomly distributed treatment group and control group30cases each. Treatment group gegenqinlianmodified decoction and the control group given hydrochloric acid alkalitreated for3days. Using SPSS13.0statistical software, according tocalculation results before and after treatment.Two groups is the same as sex,age, major symptom score and so there was no significant. To stool frequency,stool characteristics, abdominal pain as the main effect of target, comparingbetween two groups with symptoms of major inter-group. There iscomprehensive evaluation of the total efficiency and the cure rate in the totalscore before and after treatment. Record accurately the adverse events inclinical trials.Results: The results showed that the difference between two groups ofabdominal pain symptoms has statistical significance after3days treatment,(P<0.05),but it had no statistical significance between stool frequency andstool characteristics (P>0.05).After treatment,total symptom score betweentwo groups, the difference was not statistically significant. Compared on totaleffective rate, in treatment group93.3%,90.0%for the control group, twogroups was no significant difference. The cure rate in treatment group40.0%,which in the control group16.7%,there is inter-group statisticaldifference between significance of study(p <0.05).There does not appearadverse reactions in the60patients. The decoction is secure.Conclusion: Gegenqinlian modified decoction treatment of children withdiarrhea (damp-heat) can significantly improve the children with diarrhea andabdominal pain which particularly improves children more significant effect.There is no significant difference in the overall effciency,but higner cure ratecompared with the control group. It is confirmed that gegenqinlian modifieddecoction treats children with diarrhea(damp-heat)effective in the clinical. |
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