| ObjectiveMiddle Jiao where the spleen and stomach place is the pivot of Qi-activity. Tai Yin disease caused by deficiency of spleen and stomach or started by the evil, either leads insufficient of Zhong Yang, weakness of transport, cold dampness retention and disorder of ascending and decending. Zhongjing’s treatment is "to warm it","Si ni decoctions should be supplied ".Li Zhong bolus who made up of Ren Shen, Bai Zhu, Gan Jiang and Zhi Gan Cao is one of the Si ni decoctions. Regulating the spleen and stomach was put in an important place by physicians of the past dynasties in the clinic, which also is one of the key problems when my supervisor considering the herbs’choosing. At present, though there are a large number of reports of the Li Zhong decoctions, there isn’t report studying Li Zhong decoction by holistic form. This study attempts to discuss the decoction’s contemporary regularity of diagnosis and therapy, through which provide reference for standard decoction choosing in the clinic and expand the application range. Also preliminary exploring the clinical supply rule of Li Zhong decoction’s mechanism, therapy, decoction and herbs.Methodsthe study gave priority to contemporary consilia literatures, mainly collected Li Zhong decoction’s clinic literatures which published in all kinds of medical journal from1989to2011. Strictly under the inclusion and exclusion criteria,167cases were screened out. Symptoms, tongue pulse, herbs and diseases of Chinese and western medicine were included as the mainly projects. Li Zhong decoction’s contemporary rule of pattern and treatment were found out through which we can get the explicit diagnostic indices, regularity of herbs’addition and subtraction, disease notation of Chinese and western medicine etc by analysing all data of the cases, using methods of Frequency statistics analysis, Fibonacci method and The statistical analysis of the key words, which based on the data library including all standard information of the cases.Results(1) Li Zhong decoction’s general pathogenesis regularity:no significant difference in gender, above30years as the main onset age, October, March and June is the season, within half a year and more than4years are the main course range, improper diet and other factors as the major reason of disease, imbalance between Yin and Yang and endogenous "five evil" as the main basic pathogenesis, the specific mechanism mainly are deficiency-cold of spleen and stomach, failure of transportation, yang deficiency of spleen and kidney and yin-cold in excess.(2) the clinical Differentiation rule:The main symptoms are poor appetite, fatigue and weakness, cold sensation of the four limbs, abdominal distension, diarrhoea, loose stools, chills, abdominal pain, limbs not warm, pale, nausea and vomiting, dizziness, bland taste (without thirsty) and listlessness. The tongue is mainly light color, enlarged and teeth-marked. The color mainly is white, and composite coating are thin&white, white&slippery and j white&moist. The main pulses conclude sunken pulse, fine pulse, heavy-thin pulse, slow pulse, weak pulse and heavy-late pulse, within which the key words are heavy, fine, slow and weak.(3) Regularity of herbs:On average, each case employ3.84herbs of the original decoction, add with2.7herbs, each case used6.54flavours. The average dose of the original decoction in descending order is Bai Zhu>Ren Shen>Gan Jiang>Gan Cao. The main plusing herbs are Fu Zi, Fu Lin, Gui Zhi, Rou Gui, Huang Qi and Ban Xia which belong to warming, tonifying, relieving exterior syndrome, removing dampness through diuresis and promoting the circulation of qi. Decoction is the most service uniform, and the main dosage is3.(4)The main Chinese diseases are diarrhea, canker sore, hemorrhagic diseases, stomach pain, constipation and abdominal pain which are the main part of spleen and stomach diseases and syndromes. While the digestive system diseases are the most in Western medicine concluding diarrhea, canker sore, gastroenteritis, constipation, polysialia, coronary heart disease, hepatitis and hiccups.Conclusion Improper diet and other factors are the major reason of disease, and the specific mechanism mainly are deficiency-cold of spleen and stomach, failure of transportation. The therapeutic principle is warming to diffuse the cold, replenishing qi to invigorate the spleen. Li Zhong decoction (made up of Gan Jiang, Ren Shen, Bai Zhu, Gan Cao) who has the function of warming to diffuse the cold, replenishing qi to invigorate the spleen gives first place to Tonify, also achieves resolving dampness, relieving exterior syndrome and etc. Because of the remarkable effect, it deserves popularizing in the clinic. The clinical range is extensive, so that all the patients who have the characteristics of deficiency-cold of spleen and stomach can be supplied. |