Influence Of The Time Of Surgery On The Time Of Recovery In Elderly Patients Undergoing General Anaesthsia

Objective To evaluate the effects of difference surgery time on recovery time in elderly patients with general anaesthsia,and to provide the reference of reduce the recovery time and the cust during hospital.Methods67elderly patients,ages65to75years (ASA physical status I or II)who with noncardiac general anaesthsia at the First Affiliated Hospital of Guangxi Medical University during October2011to April2012were included in the study.All the objects were divided into three groups with different surgery time:under three hours group; three hours to five hours group and over five hours group.All the groups were induced with a target plasma concentration of2to3.5μg/ml of propofol (with Marsh’s pharmacokinetic model) and a target plasma concentration of2to3ng/ml of remifentanil(with Minto’s pharmacokinetic model).Tracheal intubation was facilitated by cisatracurium0.2mg/kg IV after2minutes.After anaesthesia was induced,the target plasma concentration of propofol and remifentannil were administered to maintain haemodynamics(systolic arterial blood pressure and HR increased or decreased within30%basline values) throughout the surgical procedure. cisatracurium was repeated for muscle paralysis with0.05-0.15mg/kg as necessary.The lungs were ventilated with oxygen/air(Fio20.5) to maintain an PaCO2about40mmHg.Thirty minutes before the end of surgery, fentannil0.1mg was infused.TCI was stop at the last surgical suture. Tracheal extubation was in the post anaesthsia care unit after surgery. Recorded cases were the time of surgery start and end,the time to wake up,the time of wake up-Tracheal extubation,the time to leave PACU, total dosages of propofol,liquid intravascular volume administration,hypothermia, Oxygenation index before surgery,during surgery and after surgery.Results (1)The sex ratio of the three groups,age,weight,ASA classification were not statistically significant,P<0.05.(2)One patient was sent to ICU because of hypoxemia after surgery,and was not included in our observation.(3)All the time to wake up, time of wake up-Tracheal extubation and the time to leave PACU were different in the three groups,P<0.05.Conclusion the time of Recovery was delayed when the time of surgery was longer in elderly patients undergoing noncardiac general anaesthsia.