| Purpose: To observe the clinical curative effect of Xiaoke particle and Irbesartan topatients who is in the diabetic nephropathy Ⅲ period of Qi and Yin deficiency and Stasis-Toxin syndrome, to evaluate the effectiveness of the drug.Method: According to the order of medical, group the figures with random，this methodwill meet patients whom at the diabetic nephropathy HI period of Qi and Yin deficiency andStasis-Toxin syndrome, divided each30patients into the treatment group and contrast group.In the treatment of basis diabetes，both two groups of patients were given Irbesartan,andthe treatment group add Xiaoke particle to the control group.The peirod of treatment is8weeks.Observe the changes these two groups of patients about clinical performance of beforeand after the treatment, and test the UAER, ACRr FPG(venous blood)，2hPG(fingers), andHbAlC, which before and after the treatment*Result: After eight weeks of the treatment, the total of the treatment group effectivenessis80.0%, the total of the control group effectiveness is46.7。/。,after the analysis of relatedstatistical，there are significant significance of statistical, that is, P <0.05.Conclusion: According to the suggests of clinical research, Xiaoke particle/joint emberd can obviously reduce the rate of microalbuminuira discharging.the ratio ofmicroalbuminuria/biood creatinine, these can make the patients’ glycated hemoglobin andplasma glucose drop whos in the phase III of the diabetes nephrosis.and these can make theclinical symptoms significantly reduce，and improve the effections of clinical curative，wespeculat that the mechanism of action maybe the regulate of the three materialmetabolic，which reduced the diabetic nephropathy high filtration of the kidney,and make theuirnary albumin excretion rate be reducted.this will improve the circulation of kidney anddelay the disease progression,so it is worth promoting and applying in the clinical research. |
PDF Full Text Request