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To Improve The Insulin Resistance Of Type2Diabetes Obese Patients From The Spleen

Posted on:2013-03-25Degree:MasterType:Thesis
Country:ChinaCandidate:Y Y SunFull Text:PDF
GTID:2234330374494048Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Objective:Diabetes is a group of metabolic diseases characterized by chronic hyperglycemia The genetic factors and environmental factors interaction, resulting in lack of insulin secretion and (or) insulin biological function obstacle, cause sugar metabolism disorders, at the same time with protein, fat and other metabolic abnormalities. Diabetes in people with the disease mainly for type2diabetes,85%of patients with type2diabetes combined with obesity and obese type2diabetes prevalence of all type diabetes patients. Diabetes belongs to the "xiaoke" category of traditional Chinese medicine,"xiaoke" disease with "More than three a little" for its characteristics, As early as in "huang di nei jing ", be to have recording to "xiaoke" disease. Since then every Doctor of traditional Chinese medicine on the basis of theories of huang di nei jing theory comments quite much.the treatment experience is also extremely rich. Rise living standard with the advancement of society, Modern diabetes patients presented a new characteristics, thin is no longer the typical characteristics for Diabetes patients, Obese2type diabetes patients becomes the main patient types. Therefore, to development the traditional Chinese medicine theory to services modern clinical is the essence reflect of the syndrome differentiation and treatment system. In recent years.Methods:From the perspective of modern medicine, patients with diabetes itself exists of the metabolic syndrome. Especially diabetes in obese patients relative shortage of insulin based on merger often insulin resistance. Insulin resistance is the pathology base, lipid metabolism disorder is the physical features, patients plasma free fatty acid, cholesterol, triglyceride level, low density lipoprotein often is in the high level state, through the observation of diabetes patients blood sugar, glycated hemoglobin, triglycerides, and insulin levels in the blood, patients weight, the spleen deficiency symptoms such as integral index,first of all, learn to see changes in patients with blood sugar illness; Secondly, can be estimated indirectly, according to the changes in triglycerides, insulin levels and glucose levels in insulin resistance to improve the situation. Finally, patients with spleen deficiency symptom score, compared to the integral changes before and after treatment. These indicators as well as patient weight change obtained Spleen Qi corresponding indicators as well as patients with symptoms on the role of point for further research to provide objective information. In this study, collection of Shanxi Medical College Hospital medical records met the inclusion of standard medical records of100cases were randomly divided into two groups of patients in age, gender, disease duration differences in no significant (P>0.05) were treated with western medicine alone, and in this spleen Qi (mainly Yu Ye Tang Decoction) in the treatment of Chinese medicine based on the merger, the relevant indicators in the two groups of patients before and after treatment were compared. In order to determine the use by the treatment of obese type2diabetic patients the effectiveness of the Spleen on the treatment of the spleen on the treatment of spleen Qi prescription. Results:Blood sugar before and after the treatment group, P<0.05statistically significant difference.For triglyceride treatment group and control group, P<0.05statistically significant difference, low density lipoprotein P>0.05, have no significant difference, Total cholesterol, P>0.05,have no significant difference, Total cholesterol, P>0.05, have no significant difference, The changes in Glycosylated hemoglobin P<0.05statistically significant difference., BMI changes P>0.05patients of body mass index before and after treatment no significant changes, The improvement of the spleen deficiency symptoms, the treatment group than controls significantly different, Waist circumference (WC) P>0.05, before and after treatment the change in waist circumference is not obvious, Treated from spleen deficiency in obese patients with type2diabetes, with Jianpi Yiqi prescription on blood glucose of patients with improved. For the improvement of the spleen deficiency symptoms is obvious for BMI role in the short term has not seen the obvious effect. From patients with various indicators change inferred from the Spleen on the governance of obesity with type2diabetes impose Jianpiyiqi medicine, mainly from the lipid-lowering play a role.Conclusion:1、Treated from spleen deficiency of obese type2diabetes mellitus with herbs can improve patients’ serum lipid levels.2、Treated from spleen deficiency of obese type2diabetes mellitus with herbs for hypoglycemic drugs have a supporting role.3、According to the lipid toxicity,treated from the spleen deficiency type2diabetes and obesity to insulin resistance improvement is mainly from the lipid lowering function.4、Treated from spleen deficiency of obese type2diabetes mellitus with herbs in patients with spleen deficiency symptoms improved significantly,blood lipid levels improve also more obvious, in insulin release index before and after the change was not significant under the premise of strengthening the spleen and replenishing qi, presumably for obese patients with type2diabetes primarily from reduced lipotoxicity effects play a role, from spleen deficiency treatment for obese patients with type2diabetes insulin resistance improving effects.5、Treated from spleen deficiency of obese type2diabetes mellitus with herbs, short-term inside the BMI index had no obvious change.6、Treated from spleen deficiency of obese type2diabetes and obesity on glycosylated hemoglobin in patients with improvement function.
Keywords/Search Tags:obesity, Type2diabetes, Insulin resistance, Strengthening the spleen and replenishing qi method
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