Clinical Study On Pirmary Focal Segmental Glomerulosclerosis (FSGS) Of Blood Stasis Due To Qi Deficiency With Methods Of Tonifying Qi And Invigorating The Circulation Of Blood, Dredging Collaterals And Dissipating Agglomerate

Objective: To investigate the effect of yi-qi-tong-luo-yin（YQTLY） treating pFSGSof blood stasis due to qi deficiency on the basis of western medicine treatment. To explorethe advantages and feasibility of combining traditional Chinese and western medicinetreating pFSGS and lay the foundation for further improvement.Methods:60patients with pFSGS of blood stasis due to qi deficiency were randomlydivided into2groups, experimental group and control group,each group was30cases. Patients in control group were treated by routine therapy, whilepatients in experimental group were treated by combination of YQTLY and routine therapy.The course of treatment is2months. The curative effect and the related indexes weredetermined before and after treatment, the change of patients’ clinical symptoms wasrecorded.Results: The total effective rate in the experimental group (96.67%) was higher thanthat in the control group (56.66%, p<0.01). It is significantly different between the scoresof pro-treatment and post-treatment (p<0.01) in the experimental group. There is nosignificant difference in the remission of pFSGS between the control group and theexperimental group. There were significant difference between two groups on24h urineprotein, ALB, TCH and TG after treatment (p<0.01). There were significant differencebetween before and after treatment on24h urine protein, ALB, TCH and TG (p<0.01).Conclusion: The treatment of pFSGS of blood stasis due to qi deficiency with basicmedicine and YQTLY can significantly improve the clinical performance，decrease24hurine protein, increase ALB, improve lipid metabolism. Thus the advantage of combining traditional Chinese medicine and western medicine in the treatment of the disease can beshowed.