Objective:To observe the clinical effect and safety of Jingshuyin(JSY)Formula ontreating Primary Dysmenorrhea (PD) of congealing cold and blood stasis,and to explore itsmechanism of action.Method:Choose60patients who belong to PD of congealing cold andblood stasis.Divided them randomly into test group(30cases,treated with JSYFormula),and control group(30cases,treated with Shaofuzhuyu Cranule).Both groupsstarted at7days before the menstrual period and lasted10days,a course contained3menstrual cycles.Before and after treatment,the therapeutic effects on PD,TCMsymptoms,the change of the uterine blood circulation,the blood rheology,and the PGF2αinthe menstrual blood would be compared.Results:The therapeutic effects on PD hasdifference between2groups(P<0.05).The TCM symptom of the test group and controlgroup is different(P<0.05).After the JSY Formula treatment, The uterine artery blood flowand the average flow speed were both increased,while the PIã€RIã€A/B were all decreased(P<0.05or P<0.01).the indexes of blood rheology were significantly decreased(P<0.05).The indexes of PGF2ααin the menstrual blood is deceased obviously(P<0.05).Conclusion:JSY Formula indeed has a good therapeutic effect on this disease.And tiis safe. |