Objective: To investigate clinical efficacy and mechanism of action the treatment of blood stasis type caused by cold accumulation Primary Dysmenorrheal.Methods: 50 cases of the patients with blood stasis type caused by cold accumulation primary dysmenorrhea were randomly divided into Pain-relieving and regulating menstruation formula. treatment group (treatment group) 25 cases and shaofuzhuyu Capsule (control group) of the 25 cases.Before and after medication,the therapeutic effects on PD ,TCM symdroms, pelvic blood flow resistance index changes in related indicators,and the E2,P were compared. Results: In the aspect of comprehensive curative effect the TCM symdroms of the Treatment group was 96%, the control group was72%, the two groups which were compared with had significant difference (P <0.05). in the aspect of pain Syndromes'effect, the treatment group was significantly better than the control group (P <0.05). The two groups which were compared with had significant difference (P <0.05) in the aspect of RI,PI curative effect,the treatment group was significantly better than the control group (P <0.05). The E2 level of treatment group obviously decreased(P <0.05).The P level of treatment group obviously increased(P <0.01).Conclusion: Pain-relieving and regulating menstruation formula can effectively improve the clinical symptoms and signs of the PD'patients, improve the clinical efficacy; improve pelvic blood circulation.reduce uterine artery resistance and the homeostatic equilibrium of organism and consolidate curative effect... |