The Mixture Of The Coptis Lipid-lowering Involved N The Postoperative Phlegm And Blood Stasis Syndrome Of Coronary Heart Disease

OBJECTIVE:This study of coronary heart disease by observing the the Coptis lowering mixture involved in the postoperative Phlegm each node syndrome symptom efficacy, biochemical indices, CRP and six months after PCI, myocardial oxygen consumption, the recurrence of cardiovascular events and other indicators to explorein the fight against PCI restenosis after mechanism of action.METHODS:Select May2010to October2011, Wuhan First Hospital cardiovascular medical ward in line with patients after percutaneous coronary intervention patients met the inclusion criteria, a total of60cases. Randomly divided into treatment group (Coptis lipid-lowering mixture of conventional western medicine) and the control group (conventional western medicine), of each30cases. In the control group conventional western medicine with antithrombotic, anticoagulant,lipid treatment, etc. The treatment group was added in the control group on the basis of Coptis lipid-lowering mixture. The treatment lasted three months. Respectively, before treatment and after treatment to observe the following items:angina pectoris, the main clinical symptoms, traditional Chinese medicine syndrome integral, blood lipids (TC, HDL and LDL, TG), and the CRP content changes. And after6months follow-up to calculate the difference between the two groups before treatment and after6months two groups of myocardial oxygen consumption, and were compared to the recurrence of cardiovascular events, the final statistical analysis.Result:By statistical analysis, the improvement of angina symptoms and the control group no significant difference compared by statistical analysis. After treatment, the degree of improvement in Chinese medicine symptom and improve the rate effect is significant (P<0.05). After treatment, phlegm and blood stasis card points than before treatment decreased significantly, and the treatment group than the control group decreased significantly (P <0.01). After treatment, the TC, LDL and TG levels than before treatment have decreased significantly, and the treatment group compared with the control group decreased significantly (P<0.05); After treatment, the HDL level has increased compared with before treatment (P<0.01), and the treatment group than in the control group than increased significantly (P<0.05). After treatment, the significantly lower the CRP content than before treatment, and treatment group were decreased by more obvious between the two groups have significant difference (P<0.01). After six months, two groups of myocardial oxygen consumption decreased significantly, and the treatment group than the control group decreased more significantly (P<0.01); recurrence of angina and the treatment group than the control group was significantly lower than before treatment (P<0.01).CONCLUSION:Coptis lipid-lowering mixture can significantly improve the symptoms of coronary heart disease after PCI, phlegm and blood stasis syndrome of angina and reduce TCM syndrome score; regulation of lipid metabolism, lowering blood lipids, inhibit the inflammatory response after PCI can significantly reduce the restenosisrate, which effectively prevented after PCI restenosis.