Font Size: a A A

Children With Lower Respiratory Tract Mycoplasma Pneumoniae Infection In The Evolution Of Traditional Chinese Medicine Pathogenesis And LiFeiTongLuo Fang Intervention Effectiveness Evaluation

Posted on:2013-12-21Degree:MasterType:Thesis
Country:ChinaCandidate:R R LvFull Text:PDF
GTID:2234330374994133Subject:Chinese Academy of Pediatrics
Abstract/Summary:PDF Full Text Request
Objective:To investigate the evolution of the TCM Pathogenesis of children with respiratory tract Mycoplasma pneumoniae infection. And I Lifei the Tongluo party clinical intervention, respectively, to evaluate the effectiveness of interventions in terms of clinical efficacy, before and after treatment of TCM climate and symptoms integral change. Broader ideas for the clinical syndrome in the treatment of children with respiratory tract Mycoplasma pneumoniae infection.Method:1. According to the case inclusion criteria and exclusion criteria, a total of108patients as cases of observed objects. Were randomly divided into treatment group and control group,54cases. The two groups were compared to gender, age, duration, and severity of cases, through statistical tests, differences were not significant (P>0.05) were comparable.2. Designate the performance of the card when the day of treatment or admission into the lung cold closed, wind-heat closed the lung, phlegm closed lung, Yin Hyperactivity card, lung spleen deficiency syndrome. The patients were divided into early3-7days, the medium-term,8-14days and14days late more than three groups, application syndromes probability analysis three groups of Chinese medicine syndrome.3.In the control group alone use of azithromycin treatment. The treatment group and Lung meridians party intervention on the basis of azithromycin plus azithromycin usage with the control group. Treatment group and control group treatment.4. In the course of treatment will permit type according to standard scores, evaluation once every three days. Observed two groups of clinical efficacy of clinical symptoms including fever, cough, lung signs of improvement, as well as changes in the symptom score, and calculate the total score. The two groups were compared efficiency, TCM syndrome integral climate and symptoms. Through analysis to understand the Lifei tongluo treatment the card more effective and clinical symptoms in terms of efficacy.Results:1. Climate evolution in TCM Syndrome:the comprehensive comparison of various traditional Chinese medicine syndrome types before treatment, after statistical analysis, there are very significant differences (P<0.01). Closed lungs and phlegm-heat-closed lung type early wind-heat common each accounted for55.4%and26.1%respectively; the mid-still mostly the type of wind-heat closed the Lung phlegm-heat off the lung, respectively25.0%and41.7%; late Deficiency Hyperactivity type and DLS type-based, respectively42.1%and47.4%. Treatment after seven days, four days after treatment, TCM syndrome within the two groups and between the two groups designate the type of a very significant difference (P<0.01). And prompt treatment group in the intervention role of Chinese medicine, to the phlegm-heat closed the Lung Deficiency Hyperactivity lung spleen deficiency the number of cases was significantly less than the control group.10days after treatment in two groups of TCM climate types have a very significant difference (P<0.01). Between the two groups of TCM Syndrome type of comparison, the cold closed lung and wind heat off the Lung significant difference (P<0.01). Phlegm heat closed lung Deficiency Hyperactivity and DLS-based no significant difference (P>0.05).2. In the integrated efficacy:4days after treatment, the treatment group the total efficiency of79.6%; the control group, the total efficiency of38.0%. Two sets of clinical effects have a very significant difference (P<0.01).7days after treatment, the treatment group, the total efficiency of96.3%; control group was88.9%. Two sets of clinical efficacy have a significant difference (P<0.05).10days, the treatment group and control group after treatment was100%. Two sets of clinical efficacy was no significant difference.(P>0.05).3.Syndrome score in TCM Syndrome:two groups of children in the pre-treatment total score of traditional Chinese medicine syndrome was no significant difference (P>0.05) were comparable. The two groups of children in the4days after treatment, cold closed lung and wind-heat closed the Lung card symptom scores compared with no significant difference (P>0.05). Phlegm-heat close to the Lung Deficiency Hyperactivity lung spleen deficiency syndrome score, suggesting a significant difference (P<0.05). And phlegm-heat treatment group in the treatment of closed lung type Deficiency Hyperactivi ty lung spleen deficiency type of cl inical efficacy than the control group. The two groups of children in the7days after treatment, cold evidence of closed lung type symptom scores compared, suggesting that there is significant difference (P<0.01). Wind-heat closed lung-type syndrome score there was no significant difference (P>0.05). Phlegm-heat close to the Lung Deficiency Hyperactivity type and DLS syndrome score in comparison has a very significant difference (P<0.01). And phlegm-heat treatment group in the treatment of closed lung type Deficiency Hyperactivity lung spleen deficiency type of clinical efficacy than the control group. The two groups10days after treatment in children with cold lung-type closure and wind heat closed lung-type syndrome score has a very significant difference (P<0.01). The two sets of phlegm-heat lung type closure permit Deficiency Hyperactivity lung spleen deficiency syndrome score no significant difference (P>0.05).4. In symptom score:two groups of children with the symptom score before treatment, statistical analysis, no significant difference (P>0.05) were comparable. The two groups in the first4days after treatment, cough, sputum, symptom scores more significant difference (P<0.05). Integral of fever and pulmonary signs have a very significant difference (P<0.01). And the treatment group than the control group the clinical efficacy in the treatment of cough, expectoration, fever and improvement of pulmonary signs. The two groups after treatment,7days, cough, sputum and improvement of pulmonary signs integral comparison has a very significant difference (P<0.01). Heat points was no significant difference (P>0.05). And the treatment group seven days after treatment, cough, sputum production, and improve the clinical efficacy of pulmonary signs than the control group. Due10days after treatment, children with cl inical symptoms have disappeared, so this is not a comparison of symptom scores.Conclusion:1.Evolution of TCM syndromes in children with respiratory tract Mycoplasma pneumoniae infection, initially based on the wind and heat off the lung, phlegm closed lung-based; the course of the mid-closed lung is still phlegm-heat and wind heat off the lung mainly to the yin lung cases of change of heat lung spleen deficiency deficiency gradually increased; the late multi-Deficiency Hyperactivity cards, lung and spleen deficiency syndrome and deficiency. And through the intervention role of the drug treatment group closed on the phlegm-heat the Lung Deficiency Hyperactivity lung spleen deficiency in children with more effective than the control group. Mycoplasma pneumoniae infection TCM syndromes in the evolution of the law point of view, and Lung meridians is more suitable to the patient in the course of a week later.2. Lung meridians side joint azithromycin in treatment of respiratory Mycoplasma pneumoniae infection medication after the first mid-term clinical effects are superior to the use of azithromycin in the treatment alone, no significant difference in the treatment of post-therapeutic effect. Prompted the early and mid-use and Lung through the network side to safety were not evil to improve clinical efficacy, and to mitigate the evil injury righteousness.3. Lifeitongluo Fang azithromycin to improve the symptoms have a significant effect advantage. Especially early in the treatment of cough, sputum, fever and improvement of pulmonary signs of clinical efficacy superior to the control group. Management of lung through network phlegm-heat in the treatment of closed lung Deficiency Hyperactivity license and lung spleen deficiency syndrome and are superior to the use of azithromycin in the treatment alone. Instructions the Lifei pass network side Xuanfei lower gas efficacy of Huatanzhike Chief to Yiqiyangyin heat. Worthy of our further explored.
Keywords/Search Tags:children, Mycoplasma pneumoniae, and LiFeiTongLuo Fang, azithromycin, pathogenesis, efficacy
PDF Full Text Request
Related items