Traditional Chinese Medicine Retention Enema Combined With Oral Intestinal Probiotics For The Treatment Of Ulcerative Proctitis Clinical Study

Objective： Chinese medicine retention enema combined with oralintestinal probiotics treatment the clinical curative effect of ulcerativeproctitis.The morbidity of ulcerative proctitis is rising in our country.Thecourse of this disease is long,the pathological changes happened to the rectummucosa.The changes of the primary pathology:hyperemia dropsy ordissipated in mucosa.the clinical manifestation:painful in lower abdomen,bump in anus,straining,not smooth when defecatting and so on, are all comefrom the patient`s action in chief.the system outside of the intestinal can beinconvenienced sometimes.damp and hot of intestinum crassum is on the basisof a pathogenesis from practitioner of Chinese medicine and Westernmedicine.Therapeutic method from practitioner of Chinese medicine isclearing heat and promoting diuresis hemostasis.the new-style therapeuticmethod is discussed from its curative effect and superiority,external treatmentand endotherapy,combine of local treatment and Holistic Health Care, treatingboth symptoms and root causes.at the same time this method can be comparedwith clysis of0.2%metronidazole100ml、gentamicin8myriad u fromWestern medicine.At the end a new method can be finished.The prescriptionof traditional medicine clyster is coming from Anorectal office of hospital oftraditional Chinese medicine in Hebei medicaluniversity.Constitute:Scutellaria baicalensis, Coptis chinensis, golden cypress,rhizoma bletillae, radix angelicae, Angelica sinensis, rhizoma atractylodis, theroot bark of the peony tree,Ledebouriella seseloides Wolff, Schizonepeta,pollen typhae,each is10g,decocting medicinal herbs in100ml,the drugs ofbifidobacterium species are to keep the balance of theintestinal microecology.Methods:The68patients were choosed from the strict Inclusion criteria from hospitalized or clinic:1) chronic recurrent or chronic type light, mid andsevere ulcerative proctitis2)the type of syndrome were all damp and hot inintestinum crassum3)the limit of pathological changes were all in rectum.They were all randomly divided into experimental group and matchedgroup,every group has34patients. The two groups of patients before treatmentin gender, age, course of disease classification, length, the main symptoms andsigns in five aspects were not statistically different (P>0.05).The experimentalgroup were gave100ml traditional medicine clyster,At the same time oraldrugs of bifidobacterium species1.26g,early middle three times.enemamethod:the patients with lateral position, pour warm decoction of traditionalChinese medicines into a one-time enema bags, net at the ends of the airenema bag to insertion, daub after liquid paraffin in the end of theendotracheal tube inserted into the anus, adjust speed regulator, all at a speedof5ml per minute into the rectum, enema told patients with knee chestposition after2min.To make solution fully infiltrates by the rectum, thepatients should be told to the left side after2min to hypothesis to the order ofthe right side a changing positions, finally to comfortable body position, tomake solution to absorb sufficient retention enema of time should not less than20min.the matched group were gave enema of0.2%metronidazole100ml、gentamicin8myriad u and oral drugs of willow nitrogen sulphanilamidepyridine4g,early middle three times.the enema methods are all thesame.Continuous administration two period of treatment, each course for twoweeks.Specialized examination, fill in patients with ulcerative rectitistreatment clinical observation table, according to the table for the major part ofthe signs and symptoms score.The touch and the microscopic examination ofthe rectum score by the doctor to fill out, watch and truthfully record thechange of the experimental control group two groups of patients before andafter medication, finally according to the integral before and after treatment,respectively to the total effect of main symptoms and signs to evaluate thecurative effect of the curative effect and grade of disease and determine anyadverse reactions occur. Results:two groups of patients with ulcerative rectitis in gender, age,length of course before using this drug, disease classification, main symptomsand signs of the five aspects were no statistical difference.Two observedindicators before and after treatment was statistically significant, two groupsof patients after treatment the total effective rate, light and mid ulcerativeproctitis efficient and most of the signs and symptoms.(P <0.05)Conclusion:To chronic continuous type or chronic recurrence patients withmild-to-moderate ulcerative proctitis using Chinese medicine retention enemawith intestinal probiotics in the treatment effect is better than that ofmetronidazole, gentamicin enema combined with oral of willow nitrogensulphanilamide pyridine group.Meaning: using the advantage of Chinese medicine combined with oralnon-toxic no side effects of the new treatment method of intestinal probioticsfor the prevention of ulcerative proctitis, diagnosis and treatment of opens up anew situation.