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Yangzhou University Faculty Of Metabolic Syndrome And Dyslipidemia Popular Research Status And Related Factors

Posted on:2012-03-30Degree:MasterType:Thesis
Country:ChinaCandidate:J LiFull Text:PDF
GTID:2244330395464248Subject:Nutrition and Food Hygiene
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Objectives1. To describe the prevalence of metabolic syndrome (MS) among faculty of Yangzhou University.2. To explore the influencing factors and exposure levels of MS and to provide information for early prevention and intervention.3. To explore the risk factors of dyslipidemia and propose reasonable dietary recommendations.Methods1. We investigated the faculty of Yangzhou University Medical Center by administration of dietary questionnaire and fasting blood biochemistry test, using SPSS17.0and IDF (2005) in data analysis.2. We explored the relationship between MS, MS risk factors and dietary patterns by using univariate and multivariate logistic regression analysis on the dietary pattern differences among MS victims, MS risk groups and control groups with questionnaire and biochemical test data.3. We clinically classified the blood lipid levels according to the "2007China’s prevention and treatment guideline of adult dyslipidemia" and investigated the risk factors by using univariate and multivariate logistic regression analysis.Results1. The prevalence of MS in faculty of Yangzhou University was10.62%, and it was increasing with age. The incidence of males was significantly higher than females (P<0.01). The peak age of onset for males was34~43while44~53for females. MS was more prevalent among subjects with middle or high school education level, especially those with elevated blood pressure or TG, and there was significant difference (P<0.01) among different educational levels.2. Adjusted for gender, age, educational level, occupation and other factors, the incidence of MS was affected by the family history of hypertension, hyperlipidemia, obesity, and cardiovascular disease (P<0.05).3. Multivariate logistic regression analysis showed that a bland diet, potato (2-4times/week), beer (5-6times/week), and health products to regulate blood pressure and improve fatty liver had significant influence on the incidence of MS.4. The relationship between the lipid factors and MS with OR were:TG> TC> LDL-C, and HDL_C was the negative factor of MS.5. According to multivariate logistic regression analysis, there was statistical significance comparing the dyslipidemia group with the control group in body weight, meat consumption (5-6times/week), alcohol drinking (2-3times/day), hypertension, uric acid, smoking and health products to regulate blood lipid.Conclusions1. The prevalence of MS in the faculty of Yangzhou University is relatively low and the prevalence of males is nearly3times of females. Therefore, it is recommended that in IDF standards, the threshold of males should be elevated while the threshold of female should be declined in China.2. The risk factors of MS include advanced age, a family history of hypertension, hyperlipidemia, obesity, cardiovascular disease, while drinking beer (5-6times/week) was negatively correlated with MS.3. The risk factors of dyslipidemia include overweight, meat consumption, alcohol drinking (2-3times/day), hypertension, uric acid; while smoking is negatively correlated with dyslipidemia.4. Dyslipidemia can contribute to atherosclerosis, coronary heart disease, angina, stroke and a series of chronic diseases and interventions to reduce lipid-related risk factors can prevent cardiovascular diseases.
Keywords/Search Tags:epidemiology, metabolic syndrome (MS), risk factor, dietary pattern
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