| Purpose:To compare the outcomes of small incision lenticule extraction surgery and wavefront-guided LASIK surgery in treating myopia.Methods:In this study34eyes of17patients who underwent SMILE were randomly matched to39eyes of20patients who underwent WASCA.Before surgery there were no significant differences between these two groups in spherical equivalenceã€ageã€gender and scotopic pupil diameter. All the patients were followed up for more than three months. UCVAã€BCVAã€spherical equivalenceã€contrast sensitivity without glareã€contrast sensitivity with glare and higher-order aberration beforeã€1month and3month after surgery were compared between the two groups.Results:There were no statistically significant differences in uncorrected or best corrected visual acuity and spherical equivalence after two surgical procedures(p>0.05).3months after surgery, SMILE group had a significant larger percentage than WASCA group of the eyes whose SE range in-0.50D to+0.50D(p<0.05).There were no significant differences in contrast sensitivity with or without glare between SMILE and WASCA before.1month and3months after surgery(p>0.05).Meanwhile,both groups presented a lower level of mean contrast sensitivity with or without glare comparing with preoperative data. There were no statistically significant differences in higher-order aberrations induced by SMILE and WASCA1month and3months after surgery(p>0.05).However, SMILE induced much fewer spherical aberration than WASCA(p<0.05).conclusion:Both SMILE and WASCA perform good efficiencyã€safety〠stability and predictability in treating myopia. Meanwhile SMILE induces much fewer spherical aberration and shows higher visual quality. However, the long term outcomes of SMILE still need to be evaluated. |