The Clinical Study On The Effect Of Peiyuanankun Decoction In Treating The Kidney Yin And Yang Deficiency Of Premature Ovarian Failure

Objective: To observe the clinical study on the effect of PeiYuanAnKunTanDecoction in Treating the kidney Yin and Yang deficiency of Premature OvarianFailure(POF) and discuss its mechanism. To provide a basis for further research.Method: The premature ovarian failure were randomly divided into60cases ofkidney yin and yang deficiency type: the treatment group (30cases, the oral PYANT) andthe control group (30cases, oral ZingBaoDiHuangWan with HuanShaocapsule). Observedchanges in clinical symptoms and signs of improvement in the situation, the determinationof the two groups of patients before and after treatment, E）, FSH, LH, BGP, CT, PTH andother indicators, AoAb indicators of changes in the two groups of patients before and aftertreatment, comparing treatment the treatment group and the controldifferences between thegroups. Instructions in syndrome PHAK significantly better than the control group.Description PYAKT improve the efficacy of traditional Chinese medicine syndrome, moreeffective than the control group.Result: From the integrated efficacy analysis, the healing of the treatment group was33.33%, the effective rate of16.67%, the effective rate of16.67%, with a total effectiverate of86.67%; The cure rate of the control group was3.33%, markedly effective rate of13.33%,30.00%efficiency, the total effective rate of46.62%. Two sets of combinationefficacy compared, P <0.05was statistically significant. TCM Syndrome Analysis: Thecure rate of26.67%, the remarkable efficiency of30.00%, the effective rate of30.00%, and 86.67%;10.00%of the cure rate of the control group, the remarkable efficiency of16.67%,36.67%efficiency, the total efficiency63.33%. Compare two sets of TCM syndromes, P <0.05was statistically significant. PYAKT to improve the efficacy of traditional Chinesemedicine syndrome, more effective than the control group.TCM symptom score comparedtwo groups of patients with TCM symptom score after treatment than before treatmentreduced the difference was statistically significant,P <0.01; difference between the twogroups was significant,P <0.01after treatment. From the change in symptom scores beforeand after treatment, the treatment group was significantly better than the control group.Conclusion: H-P-O function in patients PYAKT adjusted by the overall increase E2levels, increased ovarian negative feedback on the hypothalamic-pituitary axis, therebyreducing FSH and LH levels of disorder to improve the patient’s hormone levels, and dueto a series of clinical symptoms. And improve bone metabolism and to promoteanti-ovarian antibody negative.