Research On The Relationship Between Sex Hormones And Primary Urinary Stone Formation

Objectives: To investigate the causal relationship of sex hormone withprimary urinary stone formation, the reason of urinary tractstones gender differences and the safety of exogenousestrogen drugs, so as to provide a safe and effective methodfor clinical treatment and prevention of urinary stones.Methods: On the basis of the female menstrual history, gender andsuffering from urinary tract stones, not suffering fromurinary tract stones are divided into: women during thefollicular phase group, ovulation, luteal phase group, groupfrom urinary group from urinary tract stones are divided into:women during the follicular phase group, ovulation, lutealphase group, group of postmenopausal women group, malegroup, During the period of1995March to2014March,355patients diagnosed with urinary tract stonesand homogeneous not suffering from urinary tract stoneswere included in the study. among them, male urinary tractstore group41cases, control group41cases,40cases ofpostmenopausal female urinary tract stone,40cases in thecontrol group, premenopausal women during the follicularphase Stone25cases,control group42cases,32cases ofovulation stone group,27cases in the control group, theluteal phase Stone group33cases, control group34cases.Fasting, quite state of each patient were taken elbow venousblood samples, chemiluminescence method was used tomasure sample of E2、T、Prog、PRL、LH、FSH. comparativeanalysis.Results: Through the comparison of serum E2、Prog、T、FSH、LH、PRL,E2、T、Prog、FSH、LH，PRL in different betweengroups:1.E2、Prog in follicular phase, ovulation, luteal phase,postmenopause and male group is significantly different, inthe follicular phase, ovulation, luteal phase, postmenopauseand male group, of control group were higher.2. T、PRL ineach group had significantly difference, the urinary tractstones were higher.3.LH、FSH in the female ovulation, follicular, luteal phase, postmenopause group hadsignificantly difference, in the ovulation is not sufferingfrom urinary tract stones in each group was higher, whilein the follicle phase, luteal phase postmenopausal womengroup suffering from urinary tract stones was higher. LH inthe male group had significantly difference, urinary tractstone group was higher, and FSH in male group, thedifference was not significant.Conclusion:1.There exist gender differences,the ratio of male to femaleis prone to urinary tract stones.2.Postmenopausal womenthan in premenopausal women prone to urinary tract stones3.Sex hormones may be associated with urinary tract stones:the female hormones may play a role in inhibition of urinarystone formation, androgen may be a factor in promotingurinary stone formation.