Prevalence And Associated Risk Factors Of Age-related Macular Degeneration In50Years And Older Population In Shunqing District, Nanchong

Objective: To describe the prevalence of age-related maculardegeneration (AMD) in aged50years and older population in ShunQingDistrict of NanChong and to investigate the associated risk factors of AMD.Methods: Population-based cross-sectional of epidemiologicalinvestigation. Persons aged50years and older, recruited between May toOctober2013, from ShunQing District of NanChong, Sichuan province,China.2242eligible residents who aged50years and older of ShunQingDistrict,NanChong, were selected using a stratified, clustered, and randomsampling technique. All participants underwent a standardized interviewconcerning general data, physical examinations, life habits, history ofdiagnosis and treatment of eye diseases, laboratory examinations, andcomprehensive eye examinations, including digital retinal photography ofboth eyes.2photographs covering in the center of the macula and the opticnerve within45°of posterior eye fundus area were acquired in each eye withfundus camera. The diagnostic criteria was followed the international clinicalclassification systems. The the survey data were analyzed by statisticalsoftware SPSS13.0.Results: Of2242participates, whole examination were finished for2097persons, with the examination rate of93.53%.207patients (283eyes)werediagnosed as AMD，with the total prevalence rates of9.87%and thestandardized prevalence rates of9.73%. Early and late AMD prevalence rates were9.25%and0.62%, respectively, among participants, in which theprevalence of exudative AMD were0.14%. The prevalences of AMD in theage groups of50-59,60-69,70-79and no less than80were6.38%,9.27%,14.69%and17.39%, respectively. The visual acuity of late AMD wassignificantly worse than early AMD. The prevalence of bilateral blindness andlow vision were0.48%and1.45%of the AMD patients. There are eightfactors associated with AMD: age, systolic blood pressure, smoking, sunexposure, history of diabetes, cataract surgery and serum total cholesterolwere the risk factors of AMD, while the level of education was a protectivefactor.Conclusions: The prevalence of AMD in ShunQing District ofNanChong was9.87%. With the age increasing, the prevalence rate of AMDwas significantly increased. The late AMD affected vision seriously. The riskfactors of AMD included age, systolic blood pressure, smoking, sun exposure,history of diabetes, cataract surgery and serum total cholesterol, and theprotective factor was the level of education.