An Analysis Of The Prevalence And Its Risk Factors Of Gallbladder Diseases In Patents With Fatty Liver Disease

Objective：Through the research in recent years, jinan adult check-up crowd the prevalenceof fatty liver and fatty liver and gallbladder disease prevalence and risk factors, providereference for clinical prevention and treatment of the disease, in order to reduce the fatty liverwith the prevalence of gallbladder disease (gallstones, gallbladder polyps).Methods: Choose the healthy adult who receiving abdominal ultrasound examinationat Medical center of NO.456Hospital of People’s Liberation Army as the research object,fromJanuary2013to July2013.The main content of the research include:(1) physicalexamination：height,weight,waist circumference,systolic blood pressure (SBP),diastolic bloodpressure (DBP),etc，and calculate body mass index (BMI)；(2) biochemical examination:routine blood,liver meritorious service is,blood lipid series；(3) abdominal ultrasoundexamination: hepar,gallbladder,pancreas,spleen and kidney；(4) general situation: Throughquestionnaire survey to understand the Past medical history（history of hypertension anddiabetes）,lifestyle and eating habits.On the basis of relevant disease diagnosis standard,investigation in recent years, jinan check-up crowd prevalence of fatty liver and gallbladderdiseases, as well as the prevalence of fatty liver with gallbladder disease and emphaticallydiscusses the related risk factors.Results: There are a total of19394people accept abdominal ultrasound examination in ourhospital physical examination center from January2013to July2013,The male11420, female 7974, the ratio of male and female was1.37:1，age (16~94), the average age of43.20±14.41years old.(1) There was5870patients with fatty liver disease, the prevalencewas30.27%,1170patients with gallbladder diseases, the total prevalence rate was6.03%.theprevalence of FLD in male is higher than in female（35.86%/22.23%），Prevalence of men andwomen have significant difference(χ2=413.643,P<0.001)。The prevalence of Gallbladderdisease was5.95%in men and6.14%in women，there was no obvious statistical significancedifference incidence between men and women（χ2=0.301,P=0.584）.(2)Fatty liver disease andgallbladder disease prevalence increases with age，the prevalence of fatty liver and gallbladderdisease in female is higher than in male after60years old,the gallbladder disease prevalencedifference was statistically significant（χ2=14.253,P<0.001）.(3) The prevalence rate ofgallbladder disease in patients with Fatty liver disease is9.44%（554/5870）.The prevalencerate of gallbladder disease in patients without Fatty liver disease is4.55%（616/13524）.Theprevalence of gallbladder disease with fatty liver patients is significantly higher than thepatients without fatty liver disease(χ2=172.166,P<0.001).(4)The prevalence of gallbladderdisease with fatty liver patients in female(11.22%) is higher than male（8.67%），differencesbetween the two groups have statistical significance(χ2=9.481,P=0.002).After agestratification,61~70and70years of age or older age group of female prevalence than men,the P value were0.03and0.037, the rest have no obvious difference among all age groups.(5)According to the severity after the grouping5870fatty liver patients，there was nostatistically significant difference between groups in gallbladder diseaseprevalence(χ2=0.934,P=0.627).(6)The binary classification unconditioned Logistic regressionanalysis，The result shows that female, age, waist circumference, low density lipoprotein,drink tea, eat greasy food, like meat, sweet, no breakfast, often eat seafood, large number ofcells into the regression equation（P<0.05）,are risk factors of fatty liver with gallbladderdisease,the OR respectively are1.614,1.038,1.053,1.413,4.356,1.761,6.022,1.719,1.744,1.697,0.843.Conclusions:(1) According to the diagnostic criteria for fatty liver,the prevalence of fattyliver disease was30.27%in the adult population receiving physical examination from Jinan inrecent years，the previous has a rising trend,the prevalence in male is higher than in female; (2) The prevalence of gallbladder disease in patients with fatty liver disease is higher than thepatients without fatty liver disease；Female patients with fatty liver, especially older womenthan men over the age of60patients with fatty liver gallbladder disease easily;(3) Female, age,waist circumference,LDL-C, drink tea, eat greasy food, like meat, sweet, no breakfast,, ofteneat seafood, large number of cells are the risk factors of gallbladder disease in patients withfatty liver disease;(4) B ultrasonic examination can be used as a routine screening, it isimportant to early diagnosis of fatty liver and gallbladder disease, have beneficial to theprevention and treatment of fatty liver and gallbladder disease;(5) In order to prevent fattyliver and gallbladder disease, should be regular health checks, change don’t eat breakfast, highsugar, high calorie diet of bad habits, and advocate the reasonable dietary structure, eat freshvegetable and fruit more, increase dietary fiber and vitamin and so on, insist on physicalexercise. Actively develop and popularize knowledge of health education and targeted toprevent obesity, diabetes and other metabolic diseases, in order to effectively prevent thehappening of the disease.