Clinical Observation Of Wind Dry Lung In Jury Syndrome Of Post-infectious Cough With Mulberry Apricot Soup Treatment

Objective:To observe the clinical curative effect for wind dry lung injury type of Post-infectious Cough by Mulberry Apricot Decoction treatment, further verify the feasibility and advantage of traditional Chinese compound medicine in the treatment of Post-infectious Cough; at the same time, research on Mulberry apricot Decoction on airway immune regulation mechanism and to explore the internal correlation.Methods:The subject selected 70 outpatients with wind dry lung injury type of Post-infectious Cough patients, A randomized controlled study, divided into the treatment group (Mulberry Apricot Decoction) and control group (Compound Methoxyphenamine) of the 35 cases, take 7 days as 1 the course of treatment, only 2 courses. Through the observation of cough score, visual analogue score, cough relief time, evaluation of curative effect of cough times of relapse; Determination of sputum SIgA and serum IgG level, and compared before and after treatment.Results:Infection in two groups of wind dry lung injury type of Post-infectious Cough total effective rate of treatment group was 88.24%, and 84.85% in the control group, for comparison, difference (P< 0.05) is statistically significant, suggesting that the Medicine treatment the total curative effect is better. The two groups before and after the treatment of cough integral, cough degree comparison, the differences were statistically significant, suggesting that two groups were effectively relieve cough; integral comparison day after treatment, the treatment group have obvious advantages (0.38±0.60 vs 0.85±0.83. P<0.05), while in the improvement of cough severity also significantly compared with the control group (1.82±2.21 vs 3.09±2.16. P<0.05), and the night after the treatment in the two groups of integral have no significant difference (P>0.05). After the treatment, the treatment group relief time was 7.100±0.411 days, the mean recurrence times 1.29±0.49, the recurrence ratio was 20.00%; the control group relief time was 5.750±0.380 days, the mean recurrence times 1.71±0.77, the recurrence ratio is 42.86%, response duration that P is less than 0.05, the difference was statistically significant, suggesting that the treatment group in the condition "mitigation" state, the recurrence rate is more significant advantage. and the recurrence times constituent ratio P=0.05, the difference is not obvious.Between the two groups IgG level after treatment, serum IgG showed no significant differences, suggesting that the two groups had no significant effect on serum IgG. Research shows that, the treatment group can significantly increase the SIgA levels (83.20±11.39 ug/ml vs 143.27± 27.46 ug/ml.P<0.05), while the control group 82.44±12.15 ug/ml vs 93.55±27.84 ug/ml. P>0.05) was no significant change. The clinical process, the control group patients with mild adverse reactions.Conclusion:1、The good efficacy for wind dry lung injury type of Post-infectious Cough by Mulberry Apricot Decoction treatment, In the illness "ease" status, recurrence ratio and safety etc. The more obvious advantage;2、That mulberry apricot Decoction can improve the SIgA levels in the sputum, A preliminary proof of Mulberry apricot Decoction may be by the mechanism of increasing airway fluid (mucosal immune substance SIgA) which is play a role in the treatment of Post-infectious Cough.