Effect Of The Combined Treatment Of Traditional Chinese Medicine And Western Medicine Coordinate Dredge Psychology On Apoplexy Aural Syndrome ( Irascibility Type ) Patients For The Hidden Danger Of Atherosclerosis

Apoplexy Aural Syndrome as a clinical syndrome is closely related with Apoplexy. Apoplexy Aural Syndrome is a common and frequently-occurring disease in older age groups. The unusual signs and symptoms are shown in spirit, sensation, movement, language etc. Apoplexy Aural Syndrome is affected by the primary diseases as hypertension, hyperlipoidemia and hyperglycemia and Carotid atherosclerosis, Traditional Chinese medicine regards pathogens due to deficiency of vital QI, when the resistance of the body drops, exogenous pathogenic factors is much more likely to invading the body or pathogenic factors stay in the body. The continuous accumulation of pathogenic factors will endanger intracranial and extracranial vascular, even cause local inflammation of carotid artery or intracranial artery, and this can trigger Apoplexy Aural Syndrome. The increase level of low density lipoprotein cholesterol(LDL-C) or vascular cell adhesion molecule-1(VCAM-1) is the hidden hazardous factor of artery internal environment. LDL-C is the main lipid composition which is attached to the main artery intima, it is deposited in aortic wall, and form of atherosclerotic plaques; VCAM-1 is a main chemotactic factor which participate in the entire process of thrombosis and Endarteritis, and move inflammatory corpuscles arrive at sites of inflammation through the wall of a blood vessel, then cause the vascular inflammatory injury. Above all are the factors which cause Apoplexy Aural Syndrome. The appearance of premonitory symptom shows the body in a dangerous state. We should pay high attention to the appearance, Apoplexy Aural Syndrome, if not treated, is almost invariably fatal. The production of Apoplexy Aural Syndrome is associated with many factors, such as individual constitution, diet, emotion, habits and pathogenic factors invades meridian. Therefore, it’s better for us to prevent and cure Apoplexy Aural Syndrome from a whole situation. We should grasp the chance to cure Apoplexy Aural Syndrome, and prevent the progression of the disease. According to clinical experience for many years, this subject surveyed the effect of the combined treatment of traditional Chinese medicine coordinate dredge psychology on Apoplexy Aural Syndrome(irascibility type) patients for the hidden danger of Atherosclerosis, providing new ideas for the therapies of Apoplexy Aural Syndrome.Objective: To observe the effect of the combined treatment of traditional Chinese medicine and western medicine coordinate dredge psychology on apoplexy aural syndrome(irascibility type) patients for the hidden danger from the condition of symptomatic improvement before and after treatment, physical signs, emotions and carotid duplex ultrasound and the index of LDL-C and VCAM-1. To investigate the immune function mechanism of the combined treatment of traditional Chinese medicine and western medicine coordinate dredge psychology on apoplexy aural syndrome and evaluate its clinical outcomes.Methods: One hundred eighteen cases with Apoplexy Aural Syndrome and hyperactivity of liver yang syndrome were randomly divided into two groups with 59 patients in each group. 59 cases of the observation group, except routine therapy, each took Suppressing Liver Yang and Calming Wind decoction( bupleurum chinense 10 g, radices paeoniae alba 15 g, radix curcumae 20 g, rhizoma anemarrhenae 10 g, radix scrophulariae 10 g, prunella spike 15 g, Forsythia suspensa Vahl 10 g, Chinese trichosanthes 10 g, Zhi Banxia 10 g, Glycyrrhizae 5g) one dose of medicine a day, and use the decocting method to make clarified juice about 300 ml, take these twice a day. At the same time, used the ointment of Magnetitum and Cinnabari and Boswellia carterii and Myrrh(make by Boswellia carterii 10 g, Myrrh 10 g, Magnetitum and Cinnabari 10 g, cinnabar 10 g, peppermint oil) for external application a ear men and hear hui acupoint for 40 min, and applying psychological guidance(use spoken conversation to change patients in a positive way, resolving or mitigating troublesome thought, or emotions, enjoying ease of mind). 59 cases of the control group use the routine therapy, each one take Aspirin Enteric-coated Tablets 75 mg through the mouth, once a day. The patients of hypertension should add Levoamlodipine Maleate Tablets 2.5mg, once a day. The patients of hyperlipemia should add Simvastatin Tablets 5mg, twice a day. The patients of hyperglycaemia should add Metformin Hydrochloride Tablets 0.5mg, twice a day. A course for one month. We should take the patient’s blood pressure before and after treatment, and check the patients by the carotid duplex ultrasound. Collect the fasting b1 ood 3ml before and after the treatment, and separated serum by centrifugation in 1000r/min for 20 min. Use the direct method determine LDL-C on an empty stomach, use ELISA to determine the VCAM-1. Determine GLU with glucose oxidase method. Determine CHOL colourimetric method. To observe the effect of the combined treatment from the condition of symptomatic improvement before and after treatment, physical signs, emotions and carotid duplex ultrasound and the index of LDL-C and VCAM-1. All quantized data are analyzed by standard deviation( x ±s), ranked data and using χ2 inspection and t inspection.Result: Compared with the treatment group and the control group, after treated a month, there was obvious difference(P <0.05) between them. The index LDL-C and VCAM-1 on an empty stomach of the treatment group are obviously go back to the normal level. The clinical symptom, the abnormal sign, the negative mood and the ultrasonic examine abnormal item et al of the treatment group were significantly improve, which is better than the control group(P <0.05 or P<0.01). The total effective rate of the treatment group was 88.14%, the control group was 66.10%. The difference was significant(P<0.05).Conclusion: The effect of using the combined treatment of traditional Chinese medicine and western medicine coordinate dredge psychology treated apoplexy aural syndrome(irascibility type) patients were well, and prevent the patient’s condition changed for the worse. This treatment could let the index of LDL-C and VCAM-1 of the patients back to the normal level effectively. At the same time, this treatment could improve or eliminate the symptoms and physical signs, help the patients stay in a better mood, and keep the body maintain homeostasis. Reducing the damage of the arteria carotis and defending the body against pathogens to keep a better inner environment of artery and promote blood circulation.