Clinical Application Of Pituitary Adenoma Via Sphenoid Approach Surgery By Neuronavigation Multi-image-merged Techniques

Part 1The impact of Effectiveness of pituitary adenoma via sphenoid approach surgery by Neuronavigation multi-image-merged techniques uniting microscopeObjectiveThrough analyzing hospitalization days, operation time, resection rate and recurrence rate in pituitary adenoma via sphenoid approach surgery by using neuronavigation multi-image-merged techniques. investigate the impact of Effectiveness of pituitary adenoma via sphenoid approach surgery by neuronavigation multi-image-merged techniques.Method160 patients with pituitary adenoma in our department from 2013 to 2014 was analyzed retrospectively. Neuronavigation group: all patients performed thin-layer enhancement MRI T1 W, Sella turcica area CT, MRA Inspection, and using neuronavigation to multi-image-merged three-dimensional reconstruction. The control group: performed Conventional MRI scan, and operated without neuronavigation. Through analyzing both data, confirm the impact of Effectiveness of pituitary adenoma via sphenoid approach surgery by neuronavigation multi-image-merged techniques.ResultNeuronavigation multi-image-merging group: totally 60 patients, postoperatively total resection in 50 patients; average operation time is about 54 minutes; The postoperative follow-up of 1 year: the recurrence in 12 patients; average hospitalization time was 6 days.The control group: totally 100 patients, postoperatively total resection in 65 patients; average operation time is about 78 minutes; The postoperative follow-up of 1 year: the recurrence in 28 patients; average hospitalization time was 7 days.ConclusionBy applying neuronavigation multi-image-merged techniques, we could momentarily realize direction and depth of operation, help to support with accurate positioning, eliminate the difficulty of surgery operation, shorten operating time, have high value of clinical application.Part 2The impact of safety of pituitary adenoma via sphenoid approach surgery by Neuronavigation multi-image-merged techniques uniting microscopeObjectiveThrough analyzing Intraoperative blood loss, the intraoperative and postoperative complications, resection rate and recurrence rate in pituitary adenoma via sphenoid approach surgery by using neuronavigation multi-image-merged techniques. investigate the impact of safety of pituitary adenoma via sphenoid approach surgery by neuronavigation multi-image-merged techniques.Method160 patients with pituitary adenoma in our department from 2013 to 2014 was analyzed retrospectively. neuronavigation group: all patients performed thin-layer enhancement MRI T1 W, Sella turcica area CT, MRA Inspection, and using neuronavigation to multi-image-merged three-dimensional reconstruction. The control group: performed conventional MRI scan, and operated without neuronavigation. Through analyzing both data, confirm the impact of safety of pituitary adenoma via sphenoid approach surgery by neuronavigation multi-image-merged techniques.ResultNeuronavigation multi-image-merging group: totally 60 patients, Intraoperative cavernous sinus injury in 2 patients; Intraoperative cerebrospinal fluid leakage in 5 patients; The postoperatively high pressure in saddle area in 1 patient; postoperatively cerebrospinal fluid rhinorrhea in 1 patient; Transient urine collapse in 2 patients. Postoperative hypopituitarism in 2 patients. Intraoperative blood loss was about 46 ml.The control group: totally 100 patients, Intraoperative cavernous sinus injury in 8 patients; Intraoperative cerebrospinal fluid leakage in 11 patients; The postoperatively high pressure in saddle area in 5 patients; postoperatively cerebrospinal fluid rhinorrhea in 7 patient; Transient urine collapse in 10 patients; Postoperative hypopituitarism in 5 patients. Intraoperative blood loss was about 68 ml.ConclusionBy applying neuronavigation multi-image-merged techniques, we could momentarily realize direction and depth of operation, help to support with accurate positioning, eliminate the difficulty of surgery operation, shorten operating time, have high value of clinical application.Part 3The application of pituitary adenoma via sphenoid approach surgery by Neuronavigation multi-image-merged techniques uniting microscope and neuro-endoscopeObjectiveThrough analyzing the application of pituitary adenoma via sphenoid approach surgery by Neuronavigation multi-image-merged techniques uniting neuro-endoscope, investigate the application value of effectiveness and safety of pituitary adenoma via sphenoid approach surgeryMethod40 patients with pituitary adenoma in our department from 2014 to 2015 was analyzed retrospectively. Neuronavigation group: all patients performed thin-layer enhancement MRI T1 W, Sella turcica area CT, MRA inspection, and using Neuronavigation to multi-image-merged three-dimensional reconstruction, with the help of neuro-endoscope.ResultTotally 40 patients, postoperatively total resection in 36 patients. Intraoperative cavernous sinus injury in 3 patients; Intraoperative cerebrospinal fluid leakage in 3 patients; The postoperatively high pressure in saddle area in 0 patients; postoperatively cerebrospinal fluid rhinorrhea in 0 patient; Transient urine collapse in 1 patients; Postoperative hypopituitarism in 3 patients. Mean surgery time was about 58 minutes.ConclusionBy applying neuronavigation multi-image-merged techniques, we could momentarily realize direction and depth of operation virtually, help to support with accurate positioning, discriminate surrounding constitution in reality, improve surgery safety, have high value of clinical application.